Protein Alignment CG8170 and PRSS2

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 86/256 - (33%)
• Similarity: 117/256 - (45%)
• Gaps: 46/256 - (17%)

  Fly   611 RIVGGDDAGFGSFPWQAYIRIGSSRCGGSLISRRHVVTAGHCVARATP----------RQVHVTL 665
            :||||......|.|:|..:..|...|||||||.:.||:||||...|..          .::.|.|
Human    23 KIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRL 87

  Fly   666 GDY----------VINSAVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIA 720
            |::          .||:|            :|..||  |:..:....||.::.|.........::
Human    88 GEHNIEVLEGNEQFINAA------------KIIRHP--KYNSRTLDNDILLIKLSSPAVINSRVS 138

  Fly   721 PICLPEKNEDFLGKFGWAAGWG-ALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQE 784
            .|.||.. ....|.....:||| .|:.|:.. |..||.:|.||:....||..:...     |...
Human   139 AISLPTA-PPAAGTESLISGWGNTLSSGADY-PDELQCLDAPVLSQAECEASYPGK-----ITNN 196

  Fly   785 MLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWV 845
            |.|.|:..|||||||||||||::  .||.  |.|:||.||.||.:.:||:|..|...|||:
Human   197 MFCVGFLEGGKDSCQGDSGGPVV--SNGE--LQGIVSWGYGCAQKNRPGVYTKVYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	86/255 (34%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	86/255 (34%)