Protein Alignment CG8170 and PRSS1

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 83/253 - (32%)
• Similarity: 113/253 - (44%)
• Gaps: 46/253 - (18%)

  Fly   611 RIVGGDDAGFGSFPWQAYIRIGSSRCGGSLISRRHVVTAGHCVARATPRQVHVTLGDY------- 668
            :||||.:....|.|:|..:..|...||||||:.:.||:||||.    ..::.|.||::
Human    23 KIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCY----KSRIQVRLGEHNIEVLEG 83

  Fly   669 ---VINSAVEPLPAYTFGVRRIDVHPYFKFTPQADR----FDISVLTLERTVHFMPHIAPICLPE 726
               .||:|            :|..|      ||.||    .||.::.|.........::.|.||.
Human    84 NEQFINAA------------KIIRH------PQYDRKTLNNDIMLIKLSSRAVINARVSTISLPT 130

  Fly   727 KNEDFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYR 791
            . ....|.....:|||.........|..||.:|.||:....||..:...     |...|.|.|:.
Human   131 A-PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGK-----ITSNMFCVGFL 189

  Fly   792 NGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVSYVV 849
            .|||||||||||||::  .||:  |.||||.|..||.:.:||:|..|...|.|:...:
Human   190 EGGKDSCQGDSGGPVV--CNGQ--LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	83/247 (34%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	82/247 (33%)