Protein Alignment CG8170 and Hgfac

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_006504094.1
• Gene: Hgfac / 54426
• MGIID: 1859281
• Length: 658
• Species: Mus musculus
• Alignment Length: 643
• Identity: 164/643 - (25%)
• Similarity: 226/643 - (35%)
• Gaps: 213/643 - (33%)

  Fly   375 GP-ITALPQQRPQRGFYFGDTEFRTGPPAPVRQFGPQKNFQEYVGPSEYQGTRKSRYYPYKSSRS 438
            || :||.|                ..|..||.. |......|....:|.:|.:..||.|..||..
Mouse    45 GPNVTATP----------------VTPTIPVIS-GNVSTSTESAPAAETEGPQSERYPPPSSSSP 92

  Fly   439 P--RVV--------FP-----------------------TNDNVG-----------TTGPSGPA- 458
            |  :|:        ||                       |..|..           |....|||
Mouse    93 PGGQVLTESGQPCRFPFRYGGRMLHSCTSEGSAYRKWCATTHNYDRDRAWGYCAEVTLPVEGPAI 157

  Fly   459 ---GSSGPSGNG-----------VYFSDNIAFRDQNFGINELAAVQDVRNDY-SLQD-LDSASEA 507
               .:|||..||           .:.|..:||..::.|..:  ...:.|.:| .:.| ....||.
Mouse   158 LDPCASGPCLNGGTCSSTHDHGSYHCSCPLAFTGKDCGTEK--CFDETRYEYFEVGDHWARVSEG 220

  Fly   508 TSSPQSASTFKEKVDITTDTECQH----RGGTCEFFLG------------------------CWL 544
            ..........:.:.:.|..|.|..    .||||...:|                        |:|
Mouse   221 HVEQCGCMEGQARCEDTHHTACLSSPCLNGGTCHLIVGTGTSVCTCPLGYAGRFCNIVPTEHCFL 285

  Fly   545 SGGLIQGTCDGLLRGCCHRTAKSANLGSS---------------DFVGNAVDLTDL--------P 586
            ..|.       ..||    .|.:|..|.|               |.|..|| |..|        |
Mouse   286 GNGT-------EYRG----VASTAASGLSCLAWNSDLLYQELHVDSVAAAV-LLGLGPHAYCRNP 338

  Fly   587 QKNYGP-------------------------VNNE----------------PSCGISLAKQTAQR 610
            .|:..|                         |:::                |:||....|:|..|
Mouse   339 DKDERPWCYVVKDNALSWEYCRLTACESLARVHSQTPEILAALPESAPAVRPTCGKRHKKRTFLR 403

  Fly   611 -RIVGGDDAGFGSFPWQAYIRIGSSRCGGSLISRRHVVTAGHCVARATPR-QVHVTLGDYVINSA 673
             ||:||..:..||.||.|.|.||:|.|.|||:....||:|.||.|.:.|| .:.|.||.:..|..
Mouse   404 PRIIGGSSSLPGSHPWLAAIYIGNSFCAGSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRT 468

  Fly   674 VEPLPAYTFGVRR-IDVHPYFKFTPQADRFDISVLTL----ERTVHFMPHIAPICLPEKNEDF-L 732
            .:  ...|||:.: :....|..|.|  :..|:.::.|    ||.......:.||||||....| .
Mouse   469 TD--VTQTFGIEKYVPYTLYSVFNP--NNHDLVLIRLKKKGERCAVRSQFVQPICLPEAGSSFPT 529

  Fly   733 GKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERW------HRQNGINVV---IYQEMLCA 788
            |.....||||.::       :...:.||....|.:.|..      |:.:...|.   |...||||
Mouse   530 GHKCQIAGWGHMD-------EMQSSTDVSSYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCA 587

  Fly   789 GYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVS 846
            ||.:...|:|||||||||:.:|||..||.|::|.|..|....:||:|..|:..|||::
Mouse   588 GYFDCKSDACQGDSGGPLVCEKNGVAYLYGIISWGDGCGRLNKPGVYTRVANYVDWIN 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	89/249 (36%)
Hgfac	XP_006504094.1	FN2	99..145	CDD:128373	4/45 (9%)
		EGF_CA	159..194	CDD:238011	8/34 (24%)
		FN1	197..237	CDD:238018	5/41 (12%)
		EGF_CA	242..275	CDD:238011	6/32 (19%)
		Kringle	283..364	CDD:395005	18/92 (20%)
		Tryp_SPc	406..646	CDD:238113	89/251 (35%)