DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8170 and Sb

DIOPT Version :9

Sequence 1:	NP_610441.2	Gene:	CG8170 / 35908	FlyBaseID:	FBgn0033365	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster

Alignment Length:	836	Identity:	226/836 - (27%)
Similarity:	325/836 - (38%)	Gaps:	181/836 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 TAAATAATTPSTARNLYA---PHQSFSRHDDISFKDLRQRSDGTVVQSFGSYRTARQFGGYSTTA 128
            ||||...|.|.:..:|.:   |..|.|..:|         .|.   .|.|.||...:..||....
  Fly    71 TAAAALITPPDSLESLGSLGIPSSSASSSED---------DDD---MSSGFYRIPHRLEGYPQLQ 123

  Fly   129 QRRSDPAVEIIPAP-SVELPQGELITVPKQLVPTMPENVTRQGRR-----RNYMYIPLQTEGENG 187
            |.:.....:|.|.| |....:|..:.|        .|.:..:|:.     .::|:....|.....
  Fly   124 QLQRGQNFKISPKPCSFGRVEGTCMFV--------WECIKSEGKHVGMCVDSFMFGSCCTHNYTD 180

  Fly   188 SAALLQ-----LRPSRNATLSALGPPA------DGVAAVAHEFGA-DLATQGSGP-EQPPLALEL 239
            :..|.|     .||::..||....|.|      .|:..:....|| .|..:.||| .|..||...
  Fly   181 NIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPHGAGTLVIRPSGPHHQGTLARPH 245

  Fly   240 GP----ERTERSDLMAAASSTDKLEYAEPENTSRRVGFQFPSYSLKPASPFHPQAYREDNPIFGD 300
            .|    :.|..|||..:||        .|.::|.      .|.|..|.|.:|
  Fly   246 PPPYQSKPTTASDLHGSAS--------HPSSSSS------SSSSSNPNSIWH------------- 283

  Fly   301 TSAGGYEPQPYSEDASPVPPPTQYEQHETRHTRQLYFDSDTASSSFEFPGLVSNSKPHGLKLYRD 365
            ||....:.|             |::|::..|.:.      |...||     ::..:|.|.
  Fly   284 TSTQQQQQQ-------------QHQQNQQNHWQM------TTEPSF-----ITKPRPTGW----- 319

  Fly   366 DVTKFGDINGPITALPQQ--RPQRGFYFGDTEFRTGPPAPVRQFGPQKNFQEYVGPSEYQGTRKS 428
              ||.|.:|.|:.|.|.:  :|.:.....|   ||.||.|            .|.||....|..:
  Fly   320 --TKPGIVNLPMPARPSKPSKPTKKPIVYD---RTPPPPP------------SVPPSTSTSTTST 367

  Fly   429 RYYPYKSSRSPRVVFPTNDNVGTTGPSGPAGSSG--PSGNGVYFSDNIAFRDQNFGINE----LA 487
            .......:..|:...||...: :.|.|..|.||.  ||......|...:..........    ..
  Fly   368 SLIWPAQTHPPQPHRPTRPQL-SPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRRTTTPTT 431

  Fly   488 AVQDVRNDYSLQDLDSASEATSSPQSASTFKEKVDITTDTECQHRGGTCEFFLGCWLSGGLI--- 549
            ..:....:...:.....:.|||| .|.||...|...||.........          |.|::
  Fly   432 TTRRTTTNKPTRPYQRPTTATSS-SSTSTTSSKTPTTTRPISSSSSS----------SSGIVTSS 485

  Fly   550 ----QGTCDGLLRGCCHRTAKSANLGSSDFVGNAVDLTDLPQ-------KNYGPVNNEPSCGI-S 602
                |.|         |||..   |.:|....|.:..:.:|.       |......:|  ||: :
  Fly   486 QRPTQPT---------HRTPV---LATSGIETNEISDSSIPDAGALGHVKTISAARSE--CGVPT 536

  Fly   603 LAKQTAQRRIVGGDDAGFGSFPWQAYIR----IGSS---RCGGSLISRRHVVTAGHCVARATPRQ 660
            ||:  .:.|||||..|.||.:|||..:|    .|.|   ||||:||:...:.||||||......|
  Fly   537 LAR--PETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQ 599

  Fly   661 VHVTLGDYVINSAVEPLPAYTFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIAPICLP 725
            :.:.:|:|..:...|.||....||.:..|||.:.|...  .:|::::.||:.:.|.||::|||||
  Fly   600 IRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTY--EYDLALVKLEQPLEFAPHVSPICLP 662

  Fly   726 EKNEDFLGKFGWAAGWGALNPGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGY 790
            |.:...:|......|||.|:.|..| |..||.|.||::.|..|:....:.|....|....|||||
  Fly   663 ETDSLLIGMNATVTGWGRLSEGGTL-PSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGY 726

  Fly   791 RNGGKDSCQGDSGGPLM-HDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWV 845
            ..||:|||||||||||. ..::||::|.|::|.|..||....||:...:||...|:
  Fly   727 ETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	611..845	CDD:214473	97/241 (40%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	97/242 (40%)
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	97/241 (40%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	97/242 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010