Protein Alignment CG8170 and Prss48

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001001650.1
• Gene: Prss48 / 368202
• MGIID: 2685865
• Length: 312
• Species: Mus musculus
• Alignment Length: 1039
• Identity: 190/1039 - (18%)
• Similarity: 294/1039 - (28%)
• Gaps: 334/1039 - (32%)

  Fly   210 QVSMHH------SVTMQQAPPPIPVVSAATPAGTKTRHIPSSTDHKVHHHSHNVLQSNGNCGPGS 268
            ::.:.|      |:.:...|.|.|.....||   .|.|:      ||....|
Mouse   965 EIKVEHLGQCKESIELTAKPTPFPTTHRTTP---PTAHV------KVTKQRH------------- 1007

  Fly   269 KGIANHHQTSQSGATMDKMKGSSGNVSSAGNRHHHNHHQHQQQHQQQQHQPPQQQQQQQQQQPQQ 333
                .|..|:.....::.|.....:.:...:.....|.........:...||....:....:|..
Mouse  1008 ----GHRTTTPDSYVVEAMPPPRLDGARKFSSPFTTHRPTTPYKPLRTSSPPLDFDESGSGEPSG 1068

  Fly   334 QPSIVS---KPNDAPLQKDASAVIAVT--------GSAPSTAPSVAPAGANQAETAAST-AATTA 386
            ...:||   :..:.||    ...:|.|        .|..:||....|.|...|..:..| ..:|.
Mouse  1069 DDEMVSGMEESGEEPL----GTTVATTTLPTAEERSSCDNTAFGCCPDGKTAAVNSEGTNCPSTM 1129

  Fly   387 ANGGASSM--ASGAETTAGQQPQSPTDSI--EALANIKEKTTMCLVNELARYNKIQHQYRLT--- 444
            ...|...:  ..|.|.....:.:.|...:  |...:|:.     .:|||.|.:.:|..::..
Mouse  1130 RFSGFLHLDKVEGQEVFYTPEMEDPKSELFGETARSIES-----AMNELFRKSDVQKDFQSVRVR 1189

  Fly   445 ----GESGPAH-KKHF--TVMLKLGDEEYTAEGASIKKAQHKAAGD-AIAATKYKHPPARTNR-- 499
                ..|..|| :.||  .....:||    .|||.:|  |.||:.| .|...|.:....|.|.
Mouse  1190 NLSPSNSIIAHFEAHFDPDTRFNVGD----IEGALLK--QLKASKDTGIVVKKPEEENIRINNYG 1248

  Fly   500 -------RTKTGTKGNVSSFTPTVELNALAMKRGEPTV--------YTVKAVPVPASKYGGPANG 549
                   .|.|.|..:|:  |||.....::......|:        :|....|.||:
Mouse  1249 LSTVPFFTTTTTTVASVT--TPTTTTTTMSPSSAYTTLRPITTRRPFTRTTTPAPAT-------- 1303

  Fly   550 GAGGATVPPPAVAGGGRRPVEEKLAPGVAHP-------YGGAGRYSDNAWGRAAGPAGVAGA--- 604
             .....||...|:      :..:|.|....|       :||.....||.: ....|||..||
Mouse  1304 -TTAPHVPKTTVS------LMNRLGPHAHSPCDSQPCRHGGTCEEDDNDF-TCICPAGRGGAVCE 1360

  Fly   605 --------GVGGRGGMGGFHPGHQQQQQHHHHHHGHHPRDDHANRHHAPHSYHHGDGYGHHHGPA 661
                    ..||:..|     ..|..:.:|
Mouse  1361 KVIKYFIPSFGGKSYM-----AFQTMKAYH----------------------------------- 1385

  Fly   662 VPVPAVQEFYKATLRVGERTFLGEGHTPQAARHDAAARALEVLKPLTMEGAEGKGKAGDAAANGD 726
             .|....||                            ||.|:...|...|.:.|
Mouse  1386 -TVRIAMEF----------------------------RASEMTGILLYNGQKSK----------- 1410

  Fly   727 AASSSDGTSVDGLDPNAELKSPISLVHEIAVQRSLSVVFEVISEKGPPHMTVFVTQCKVGTIVTE 791
                .|..|:..::...||:....       ..:.||:.:|:.:.|..|..|.|...:...:..:
Mouse  1411 ----KDFLSLTLVEGYVELRFNTG-------SGTASVISKVLVKPGRWHQLVVVRNRRNAMLSVD 1464

  Fly   792 GEGTGKKLSKKRAAEKMLEELRKLQKAEQQLNPSPWGEGSPGGQGGEKRKSNAKAAPSATADGAT 856
            .|                              ||..|:..||..|   ...:.........|..:
Mouse  1465 NE------------------------------PSVEGQSPPGTDG---LNLDTDLFIGGVLDDMS 1496

  Fly   857 AKKKARNLIKEKSVADVAEKENPISRLMQIQQARKEKQPVYTLQENDRPAVGRRRQFTIEVSAGG 921
            |..|.|..:....|..:        |::.:...      ||.||||     |....:...:...|
Mouse  1497 ADVKERTSVSAGLVGCI--------RMLDVNNL------VYNLQEN-----GGSVLYGSAIGECG 1542

  Fly   922 RQATGVGMTKKAAKWNAAEALLIEL----GFT-PSEAKAGAPAGGDGASANKENQ---SGAANDS 978
            .........|..|.....||.:...    ||: |:.|.|..|...:........|   .|.....
Mouse  1543 NNPCLPNPCKNGASCQVKEAEIFHCKCVNGFSGPTCADAHNPCDPNKCHPPSRCQVLPEGGYKCE 1607

  Fly   979 SPTG--GKRSRKVRFQEDPGNS-VPTATHITPAVTVANGANQVKAESTND-------SMNDSIAS 1033
            .|.|  |:...||   .|.|.: :|..|        .:...::|...|.:       ||...:.:
Mouse  1608 CPMGREGRHCEKV---SDKGGAFIPYFT--------GDSFLELKGLHTYNQDLRQKFSMTIVLLA 1661

  Fly  1034 NDSMGTNSSGVSSTSSVAPKADIGAKKEQLLYLA---QLLKFEVQFSDFPKGNHGEYLTLVILST 1095
            |||.|........|..          |...:.|:   .:|:|..   |..||      ..||.|.
Mouse  1662 NDSKGMIFYNGQKTDG----------KGDFISLSLNDGILEFRY---DLGKG------PAVIRSK 1707

  Fly  1096 EPPQLCHGSGASLQESHDEAARGALEILSKIGLH----------NVKPKAPAGSAPDDTAAATA 1149
            |..:|...:..:|:.:   :.:|.:.|..|..:.          |:|.....|.|||....|.|
Mouse  1708 EKIKLNEWNTVNLERA---SRKGEISINGKDPVRGEAPNQHTDLNLKESLFVGGAPDFRKVARA 1768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	30/233 (13%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113