DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8170 and prss60.3

DIOPT Version :9

Sequence 1:	NP_610441.2	Gene:	CG8170 / 35908	FlyBaseID:	FBgn0033365	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	262	Identity:	90/262 - (34%)
Similarity:	127/262 - (48%)	Gaps:	25/262 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   599 CGISLAKQTAQRRIVGGDDAGFGSFPWQAYI---RIGSSRCGGSLISRRHVVTAGHCVARATPRQ 660
            ||    :.....|||||.:|..||:|||..:   :.|...|||||||...|:||.||::..:
Zfish    27 CG----QAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAAHCLSGVS--- 84

  Fly   661 VHVTLGDYVINSAVEPLPAY--TFGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIAPIC 723
             ..||..|:.....:.:..|  :..|.:..||.  .:....:..||::|.|...|.|..:|.|:|
Zfish    85 -ETTLVVYLGRRTQQGINIYETSRNVAKSFVHS--SYNSNTNDNDIALLRLSSAVTFTNYIRPVC 146

  Fly   724 LPEKNEDF-LGKFGWAAGWGALNPGSRL-RPKTLQAVDVPVIENRICERWHRQNGI--NVVIYQE 784
            |..:|..: .|...|..|||.:..|..| .|..||...:||:.|..|      |.:  :..:...
Zfish   147 LAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC------NALLGSGTVTNN 205

  Fly   785 MLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWVSYVV 849
            |:|||...||||:||||||||::......|...|:.|.||.||....||:|..||:...|:|..:
Zfish   206 MICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKI 270

  Fly   850 GL 851
            .|
Zfish   271 SL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	611..845	CDD:214473	85/242 (35%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	85/242 (35%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	86/244 (35%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100