DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8170 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_610441.2	Gene:	CG8170 / 35908	FlyBaseID:	FBgn0033365	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	560	Identity:	140/560 - (25%)
Similarity:	214/560 - (38%)	Gaps:	143/560 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   376 PITALPQQRPQRGFYFGDTEFRTGPP--APVRQFGPQKNFQEYVGPSEYQGTRKS--RYYPYKSS 436
            |..|.||..|.          ||.||  :|.|...||.: .....|:.....|.|  |..|.:||
  Rat    20 PARASPQASPA----------RTPPPQASPARASPPQAS-PARASPARASPVRASPARAPPSRSS 73

  Fly   437 -------------RSP-RVVFPTNDNVGTTGPSGPAGSSGPSGNGVYFSDNIAFRDQNF------ 481
                         .|| ||.......|||...:.|| .|.|:......|..::|...::
  Rat    74 SGRSSSARSASTTSSPTRVYLVRAIPVGTVIRASPA-RSAPATRATRESPGLSFPKFSWQETQRQ 137

  Fly   482 -----------------------------------------------GINELAAVQD----VRND 495
                                                           |:.:.....|    ||.|
  Rat   138 LPLIGCVLLLISLVISLILLFYFWRGHTGIKYKEPLESCPKHAVRCDGVVDCKMKSDELGCVRFD 202

  Fly   496 Y--SLQDLDSASEATSSPQSASTFKEKVDITTDTE--CQHRGGTCEFFLGCWLSGGLIQGTCDGL 556
            :  ||..:.|.|.....|..:|::.:     ||:|  ||..|                   .|..
  Rat   203 WDKSLLKVYSGSSGEWLPVCSSSWND-----TDSERTCQQLG-------------------FDSA 243

  Fly   557 LR--GCCHRTAKSANLGS--SDFVGNAVDLTDLPQKNYGPVNNEPSCGISLAKQTAQRRIVGGDD 617
            .|  ...||...|:.|.|  :..:..::..::.|.:.|..:.. ..||:    :....|||||..
  Rat   244 YRTTEVAHRDVTSSFLLSEYNSTIQESLTRSECPSRRYVSLQC-AHCGL----RAMTGRIVGGAL 303

  Fly   618 AGFGSFPWQAYIRIGSSR-CGGSLISRRHVVTAGHCVARATPRQVHVTLGDYVINSAVEPLPAYT 681
            .....:|||..:..|::. |||:||..:.|:||.||.. .|..::......|...|.:..||. .
  Rat   304 TSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFF-VTREKILEGWKVYAGTSNLHQLPE-A 366

  Fly   682 FGVRRIDVHPYFKFTPQADRFDISVLTLERTVHFMPHIAPICLPEKNEDF-LGKFGWAAGWGALN 745
            ..:.:|.::.  .:|.:.|.:||:::.|.:.:....||.|.|||...:.| |.:..|..|:|...
  Rat   367 ASISQIIING--NYTDEQDDYDIALVRLSKPLTLSAHIHPACLPLHGQTFGLNETCWITGFGKTK 429

  Fly   746 PGSRLRPKTLQAVDVPVIENRICERWHRQNGINVVIYQ-----EMLCAGYRNGGKDSCQGDSGGP 805
            .........|:.|.|.:|:.:.|.        :.::|.     .|:|||...||:||||||||||
  Rat   430 ETDEKTSPFLREVQVNLIDFKKCN--------DYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGP 486

  Fly   806 LMHDKNGRWYLIGVVSAGYSCASRGQPGIYHSVSKTVDWV 845
            |:.::|.||||.||.|.|..|..:.:||:|..|::.:.|:
  Rat   487 LVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	611..845	CDD:214473	78/240 (33%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	78/241 (32%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964	17/59 (29%)
		SRCR_2	203..292	CDD:292133	23/117 (20%)
		SRCR	216..288	CDD:278931	17/96 (18%)
		Tryp_SPc	297..526	CDD:214473	78/240 (33%)
		Tryp_SPc	298..526	CDD:238113	77/239 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910