Protein Alignment CG8170 and F9

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_000124.1
• Gene: F9 / 2158
• HGNCID: 3551
• Length: 461
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 116/411 - (28%)
• Similarity: 182/411 - (44%)
• Gaps: 81/411 - (19%)

  Fly   502 DSASEATSSPQSASTF-KEKVDITTDTECQH----RGGTCEFFLG---CWLSGGLIQGTCD---- 554
            :.|.|...:.:..:.| |:.||   ..:|:.    .||:|:..:.   ||...|.....|:
Human    72 EEAREVFENTERTTEFWKQYVD---GDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELDVT 133

  Fly   555 -GLLRGCCHRTAKSANLGSSDFVGNAVDLTDLP--QKNYGPVNNEPSCGISLAKQTAQ------- 609
             .:..|.|.:..|  |...:..|.:..:...|.  ||:..|....| ||.....||::
Human   134 CNIKNGRCEQFCK--NSADNKVVCSCTEGYRLAENQKSCEPAVPFP-CGRVSVSQTSKLTRAETV 195

  Fly   610 -----------------------------RRIVGGDDAGFGSFPWQAYIRIG--SSRCGGSLISR 643
                                         .|:|||:||..|.||||..:. |  .:.||||:::.
Human   196 FPDVDYVNSTEAETILDNITQSTQSFNDFTRVVGGEDAKPGQFPWQVVLN-GKVDAFCGGSIVNE 259

  Fly   644 RHVVTAGHCVARATPRQVHVTLGDYVINSAVEPLPAYTFGVRR-IDVHPYFKFTPQADRF--DIS 705
            :.:|||.|||  .|..::.|..|::.|...     .:|...|. |.:.|:..:....:::  ||:
Human   260 KWIVTAAHCV--ETGVKITVVAGEHNIEET-----EHTEQKRNVIRIIPHHNYNAAINKYNHDIA 317

  Fly   706 VLTLERTVHFMPHIAPICLPEK--NEDFLGKF--GWAAGWGALNPGSRLRPKTLQAVDVPVIENR 766
            :|.|:..:....::.|||:.:|  ...|| ||  |:.:|||.:....| ....||.:.||:::..
Human   318 LLELDEPLVLNSYVTPICIADKEYTNIFL-KFGSGYVSGWGRVFHKGR-SALVLQYLRVPLVDRA 380

  Fly   767 ICERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGYSCASRGQ 831
            .|.|     .....||..|.|||:..||:||||||||||.:.:..|..:|.|::|.|..||.:|:
Human   381 TCLR-----STKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGK 440

  Fly   832 PGIYHSVSKTVDWVSYVVGLT 852
            .|||..||:.|:|:.....||
Human   441 YGIYTKVSRYVNWIKEKTKLT 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	85/242 (35%)
F9	NP_000124.1	GLA	28..92	CDD:214503	4/19 (21%)
		EGF_CA	93..129	CDD:238011	8/38 (21%)
		FXa_inhibition	134..170	CDD:464251	8/37 (22%)
		Tryp_SPc	227..457	CDD:238113	85/244 (35%)