DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8170 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_610441.2	Gene:	CG8170 / 35908	FlyBaseID:	FBgn0033365	Length:	855	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	346	Identity:	94/346 - (27%)
Similarity:	144/346 - (41%)	Gaps:	78/346 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   541 GCWLSGGLIQGTC-----DGLLRGCCHRTAKSA-------------NLGSSDFVGNAVDLTDLPQ 587
            |.|.|      .|     :.|.:..|.:....:             ||..:...||:.:|.
Mouse   119 GTWAS------VCFDNFTEALAKTACRQMGYDSQPAFRAVEIRPDQNLPVAQVTGNSQELQ---- 173

  Fly   588 KNYGPVNNEPSC---------GISLAKQTAQRRIVGGDDAGFGSFPWQAYIRIGSSR-CGGSLIS 642
                ..|...||         .:...|.....|:|||.:|...|:|||..|:..... ||||::.
Mouse   174 ----VQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILD 234

  Fly   643 RRHVVTAGHCVAR-ATPRQVHVTLGDYVINSA----------VEPLPAYTFGVRRIDVHPYFKFT 696
            ...::||.||..: .......|..|..::.::          .||.|.|          |..|
Mouse   235 PHWILTAAHCFRKYLDVSSWKVRAGSNILGNSPSLPVAKIFIAEPNPLY----------PKEK-- 287

  Fly   697 PQADRFDISVLTLERTVHFMPHIAPICLPEKNEDFLGKFG-WAAGWGALNP-GSRLRPKTLQAVD 759
                  ||:::.|:..:.|...:.|||||..:|..:.... |..|||.... |.::....||| .
Mouse   288 ------DIALVKLQMPLTFSGSVRPICLPFSDEVLVPATPVWVIGWGFTEENGGKMSDMLLQA-S 345

  Fly   760 VPVIENRICERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGVVSAGY 824
            |.||::..|   :.::.....:..||||||...||||:||||||||||:..: :|.::|:||.|:
Mouse   346 VQVIDSTRC---NAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLMYHSD-KWQVVGIVSWGH 406

  Fly   825 SCASRGQPGIYHSVSKTVDWV 845
            .|.....||:|..|:..::|:
Mouse   407 GCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	611..845	CDD:214473	78/247 (32%)
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	78/248 (31%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335	14/89 (16%)
		Tryp_SPc	202..427	CDD:214473	78/247 (32%)
		Tryp_SPc	203..430	CDD:238113	78/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910