Protein Alignment CG8170 and KLK11

DIOPT Version :10

• Sequence 1: NP_610441.2
• Gene: CG8170 / 35908
• FlyBaseID: FBgn0033365
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 89/287 - (31%)
• Similarity: 133/287 - (46%)
• Gaps: 67/287 - (23%)

  Fly   601 ISLAKQT----AQRRIVGGDDAGFGSFPWQAYIRIGSSR--CGGSLISRRHVVTAGHC----VAR 655
            |.||..|    .:.||:.|.:....|.||||.: ...:|  ||.:||:.|.::||.||    |:.
Human    39 ILLALATGLVGGETRIIKGFECKPHSQPWQAAL-FEKTRLLCGATLIAPRWLLTAAHCLKPWVSL 102

  Fly   656 ATPRQVHVT------------LGDYVIN----------------SAVEPLPAYTFGVRRIDVHPY 692
            .:|  .||:            |..|:::                :|.|..|           ||.
Human   103 TSP--THVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP-----------HPG 154

  Fly   693 FKFT-PQAD-RFDISVLTLERTVHFMPHIAPICLPEKNEDFLGKFGWAAGWGAL-NPGSRLRPKT 754
            |..: |..| |.||.::.:...|.....:.|:.|..:... .|.....:|||:. :|..|| |.|
Human   155 FNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT-AGTSCLISGWGSTSSPQLRL-PHT 217

  Fly   755 LQAVDVPVIENRICERWHRQNGINVVIYQEMLCAGYRNGGKDSCQGDSGGPLMHDKNGRWYLIGV 819
            |:..::.:||::.||..:..|     |...|:||..:.||||||||||||||:.:::    |.|:
Human   218 LRCANITIIEHQKCENAYPGN-----ITDTMVCASVQEGGKDSCQGDSGGPLVCNQS----LQGI 273

  Fly   820 VSAGYS-CASRGQPGIYHSVSKTVDWV 845
            :|.|.. ||...:||:|..|.|.|||:
Human   274 ISWGQDPCAITRKPGVYTKVCKYVDWI 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8170	NP_610441.2	Tryp_SPc	612..846	CDD:238113	84/272 (31%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	84/271 (31%)