Protein Alignment CG13744 and PRSS27

DIOPT Version :10

• Sequence 1: NP_610439.1
• Gene: CG13744 / 35906
• FlyBaseID: FBgn0033363
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 88/269 - (32%)
• Similarity: 134/269 - (49%)
• Gaps: 26/269 - (9%)

  Fly   128 CGVPRTAQNTLQKRIIGGRPAQFAEYPWQAHI-RIAEYQCGGVLISANMVATAAHCIQQAHLADI 191
            ||.||     :..|::||:..|..|:|||..| |...:.|||.||:...|.|||||.:  :.::.
Human    26 CGRPR-----MLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFR--NTSET 83

  Fly   192 TVYLGELDTQDLGHIHEPLPVEKHGVLQKIIHPRFN--FRMTQPDRYDIALLKLAQPTSFTEHIL 254
            ::|...|..:.|   .:|.|   |.:..::.....|  ::.|.... |:||::|..|..||.:||
Human    84 SLYQVLLGARQL---VQPGP---HAMYARVRQVESNPLYQGTASSA-DVALVELEAPVPFTNYIL 141

  Fly   255 PICLPQYPIRLIGRKGL---IAGWGKTEAHMGHAGTNMLQVASVPIITTLDC-IRWHESKQINVE 315
            |:|||...:  |...|:   :.|||............:||..:||||.|..| :.:.:..:...:
Human   142 PVCLPDPSV--IFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQ 204

  Fly   316 ---IKAEMFCAGHSDGHMDACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTV 377
               ||.:|.|||..:|..|||.||||||||......::..|:.|.|.||...::||:|..|....
Human   205 PKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHH 269

  Fly   378 RWIQEVVAR 386
            .||..::.:
Human   270 NWIHRIIPK 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	83/250 (33%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	83/249 (33%)