DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	354	Identity:	108/354 - (30%)
Similarity:	158/354 - (44%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 NKWLFSCCVAETQHPHQQQHHSPS--------SPLANLVDYGKLKLNL--------NSLPKRIML 113
            |.|...|..:.|     |||...:        ||:.:.:..|.|..:|        .:.|:....
Zfish   134 NTWKSVCSESFT-----QQHAETACQLLGYSVSPVFSSIAVGPLPSDLKISFCMVGTTKPQTFQS 193

  Fly   114 RRRDDNEL-------LNPKPECGVPRTAQNTLQKRIIGGRPAQFAEYPWQAHIRIA-EYQCGGVL 170
            ...|....       |:...:||:.|.     |.||:||:.|..|.:|||..::.: ::.|||.|
Zfish   194 AVSDRKVCSTGTVISLSCSADCGLSRN-----QDRIVGGKDADIANWPWQVSLQYSGQHTCGGSL 253

  Fly   171 ISANMVATAAHCIQ---QAHLADITVYLG--ELDTQDLGHIHEPLPVEKHGVLQKIIHPRFNFRM 230
            ::.|.|.|||||..   :..|:..||..|  .|.:....::.|             |....|::.
Zfish   254 VTPNWVVTAAHCFNGDGRKALSRWTVVSGITYLSSTPSSYVKE-------------IIVNSNYKP 305

  Fly   231 TQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLIGRKGL-IAGWGKTEAHMGHAG---TNMLQ 291
            .:.| :||.::||..|.:.:|...|:|||...:.|.|..|| :.|||    ||...|   ::|||
Zfish   306 AESD-FDITMIKLQSPITLSESRRPVCLPPQNLGLKGGDGLVVTGWG----HMAEKGGSLSSMLQ 365

  Fly   292 VASVPIITTLDCIRWHESKQI-NVEIKAEMFCAGHSDGHMDACLGDSGGPLVIKERGRFVLVGIT 355
            .|.:.:|.:..|    .|..: ...|...|.|||...|.:|||.|||||||| ....|:||||:.
Zfish   366 KAQIQVIDSAQC----SSPTVYGSSITPRMICAGVMAGGVDACQGDSGGPLV-HLADRWVLVGVV 425

  Fly   356 SAGFGCGVDHQPGIYHNVQKTVRWIQEVV 384
            |.|.||.....||:|.||.:.:.|...|:
Zfish   426 SWGVGCARPGFPGVYTNVDQMLDWAHSVM 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	87/249 (35%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	87/251 (35%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335	17/88 (19%)
		Tryp_SPc	223..449	CDD:214473	87/248 (35%)
		Tryp_SPc	224..449	CDD:238113	86/247 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910