DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001028824.2	Gene:	Tmprss11d / 64565	RGDID:	620654	Length:	417	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	93/301 - (30%)
Similarity:	145/301 - (48%)	Gaps:	42/301 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 SPSSPLANLVDYGKLKLNLNSLPKRIMLRRRDDNELLNPKPECGVPRTAQNTLQKRIIGGRPAQF 150
            :||:.:.:|.|                   :|...:|.  .|||.........::|||||..|:.
  Rat   151 APSNEITSLTD-------------------QDTENVLT--QECGARPDLITLSEERIIGGTQAET 194

  Fly   151 AEYPWQAHIRIAE-YQCGGVLISANMVATAAHCIQQ-AHLADITVYLGELDTQDLGHIHEPLPVE 213
            .::|||..:::.. :.|||.|||...|.|||||.:. ::....|...|      :..|...|.|.
  Rat   195 GDWPWQVSLQLNNVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTATFG------VSTISPRLRVR 253

  Fly   214 KHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLI-GRKGLIAGWGK 277
            ...:|   .|..:| .:|:.:  |||:::|.:|.:||.:|..:|||.....:| .....:.|||.
  Rat   254 VRAIL---AHAEYN-SITRDN--DIAVVQLDRPVTFTRNIHRVCLPAATQNIIPDSVAYVTGWGS 312

  Fly   278 TEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMFCAGHSDGHMDACLGDSGGPLV 342
            . .:.|:..|| ||...|.|:::..|   :|.......:...|.|||...|.:|||.||||||||
  Rat   313 L-TYGGNTVTN-LQQGEVRIVSSEVC---NEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGPLV 372

  Fly   343 IKERGR-FVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQE 382
            .::..| :.:|||.|.|:.||:.::||:|..|.....||::
  Rat   373 QEDTRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQ 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	82/242 (34%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	83/245 (34%)
Tmprss11d	NP_001028824.2	SEA	48..150	CDD:396113
Tmprss11d	NP_001028824.2	Tryp_SPc	186..414	CDD:238113	83/245 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910