Protein Alignment CG13744 and LPA

DIOPT Version :10

• Sequence 1: NP_610439.1
• Gene: CG13744 / 35906
• FlyBaseID: FBgn0033363
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_005568.2
• Gene: LPA / 4018
• HGNCID: 6667
• Length: 2040
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 113/391 - (28%)
• Similarity: 172/391 - (43%)
• Gaps: 95/391 - (24%)

  Fly    30 LGVPAE--CVHQSGVWPCKLSFSCWLQG--GKHA---KGCGSNKWLFSCCVAETQHPHQQQHHSP 87
            ||.|:|  |:..:|            :|  ||.|   .|....:|       ..|.||:   ||.
Human  1712 LGPPSEQDCMFGNG------------KGYRGKKATTVTGTPCQEW-------AAQEPHR---HST 1754

  Fly    88 SSPLANLVDYGKLKLNLNSLPKRIMLRRRDDNEL-------LNPKP---------------ECGV 130
            ..|..|  .:..|:.|         ..|..|.::       :||:.               :||.
Human  1755 FIPGTN--KWAGLEKN---------YCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSFDCGK 1808

  Fly   131 PRTAQNTLQKRIIGGRPAQFAEYPWQAHI--RIAEYQCGGVLISANMVATAAHCIQQ-AHLADIT 192
            |:.........|:||..|....:|||..:  |..::.|||.|||...|.|||||::: :..:...
Human  1809 PQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYK 1873

  Fly   193 VYLGELDTQDLGHIHEPLPVEKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPIC 257
            |.||         .|:.:.:|.|  :|:|...|.   ..:|.:.|||||||::|...|:.::|.|
Human  1874 VILG---------AHQEVNLESH--VQEIEVSRL---FLEPTQADIALLKLSRPAVITDKVMPAC 1924

  Fly   258 LPQYPIRLIGR-KGLIAGWGKTEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMF 321
            ||.....:..| :..|.|||:|:   |..||.:|:.|.:.:|....|..:            :..
Human  1925 LPSPDYMVTARTECYITGWGETQ---GTFGTGLLKEAQLLVIENEVCNHY------------KYI 1974

  Fly   322 CAGHSDGHMDACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEVVAR 386
            ||.|.....|:|.||||||||..|:.:::|.|:||.|.||...::||:|..|.:.|.||:.::..
Human  1975 CAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRN 2039

  Fly   387 N 387
            |
Human  2040 N 2040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	84/244 (34%)
LPA	NP_005568.2	Kringle	28..105	CDD:395005
		Kringle	142..219	CDD:395005
		Kringle	256..333	CDD:395005
		Kringle	370..447	CDD:395005
		Kringle	484..561	CDD:395005
		Kringle	598..675	CDD:395005
		Kringle	712..789	CDD:395005
		Kringle	826..903	CDD:395005
		KR	938..1019	CDD:214527
		Kringle	1054..1131	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1147..1166
		KR	1166..1246	CDD:214527
		KR	1272..1352	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1365..1388
		KR	1386..1466	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1476..1497
		KR	1500..1581	CDD:214527
		KR	1614..1695	CDD:214527
		Kringle	1720..1799	CDD:395005	21/111 (19%)
		Tryp_SPc	1820..2034	CDD:238113	83/242 (34%)