Protein Alignment CG13744 and KLKB1

DIOPT Version :10

• Sequence 1: NP_610439.1
• Gene: CG13744 / 35906
• FlyBaseID: FBgn0033363
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 102/311 - (32%)
• Similarity: 150/311 - (48%)
• Gaps: 64/311 - (20%)

  Fly   100 LKLNLNSLPKRI------------MLRRRDDNELLNPKPECGVPRTAQNTLQKRIIGGRPAQFAE 152
            |:|:::..|.||            .|....||.:...|            ...||:||..:.:.|
Human   360 LRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTK------------TSTRIVGGTNSSWGE 412

  Fly   153 YPWQAHIRI----AEYQCGGVLISANMVATAAHCIQQAHLADI-TVYLGELDTQDLGHIHEPLPV 212
            :|||..:::    ..:.|||.||....|.|||||.....|.|: .:|.|.|:..|   |.:..|.
Human   413 WPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSD---ITKDTPF 474

  Fly   213 EKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLIGRKG------- 270
            .:  :.:.|||.  |::::: ..:||||:||..|.::||...|||||.        ||
Human   475 SQ--IKEIIIHQ--NYKVSE-GNHDIALIKLQAPLNYTEFQKPICLPS--------KGDTSTIYT 526

  Fly   271 --LIAGWG--KTEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMFCAGHSDGHMD 331
              .:.|||  |.:..:    .|:||..::|::|..:|    :.:..:.:|...|.|||:.:|..|
Human   527 NCWVTGWGFSKEKGEI----QNILQKVNIPLVTNEEC----QKRYQDYKITQRMVCAGYKEGGKD 583

  Fly   332 ACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQE 382
            ||.||||||||.|..|.:.||||||.|.||....|||:|..|.:.:.||.|
Human   584 ACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	92/257 (36%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519	5/25 (20%)
		Tryp_SPc	402..632	CDD:238113	89/253 (35%)