DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	89/259 - (34%)
Similarity:	131/259 - (50%)	Gaps:	23/259 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 ECGVPRTAQNTLQKRIIGGRPAQFAEYPWQAHIRI-AEYQCGGVLISANMVATAAHCIQQAHLAD 190
            :||  ::.:.|   |::||..|....:|||..|:. .::.|||.::..:.:.|||||.::  ..|
  Rat   236 DCG--KSLKTT---RVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRK--YLD 293

  Fly   191 ITVYLGELDTQDLGHIHEPLPVEKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILP 255
            ::.:.....:..||: ...|||.|..:.:.  :|      .||...||||:||..|.:|:..:.|
  Rat   294 VSSWKVRAGSNKLGN-SPSLPVAKIFIAEP--NP------LQPKEKDIALVKLKMPLTFSGSVRP 349

  Fly   256 ICLPQYPIRLIGRKGL-IAGWGKTEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAE 319
            ||||.....||....: :.|||.||.:.|.....:|| |||.:|   |..|.:.......|:.|.
  Rat   350 ICLPFSDEELIPTMPVWVIGWGFTEENGGKMSDTLLQ-ASVQVI---DSARCNAEDAYQGEVTAG 410

  Fly   320 MFCAGHSDGHMDACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEV 383
            |.|||...|..|.|.|||||||:. ...::.:|||.|.|:|||....||:|..|...:.||..|
  Rat   411 MLCAGTPQGGKDTCQGDSGGPLMY-HYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNV 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	83/240 (35%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	84/242 (35%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	0/1 (0%)
		Tryp_SPc	245..470	CDD:214473	83/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910