DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and PRSS41

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001382429.1	Gene:	PRSS41 / 360226	HGNCID:	30715	Length:	334	Species:	Homo sapiens

Alignment Length:	406	Identity:	111/406 - (27%)
Similarity:	160/406 - (39%)	Gaps:	120/406 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LCLLLLICQSSPSQANILNTLLGVPAEC-VHQSGVWPCKLSFSCWLQGGKHAKGCGSNKWLFSCC 72
            |.|.||:.::.          ||.|.|. ..|:|            .|.....|.|..:..| .|
Human     7 LLLALLLARAG----------LGKPGELGALQAG------------PGAARRPGGGGREGHF-LC 48

  Fly    73 VAETQHPHQQQHHSPSSPLANLVDYGKLKLNLNSLPKRIMLRRRDDNELLNPKPECGVPRTAQNT 137
            .||:|                                        :.|||:  ..||     ...
Human    49 PAESQ----------------------------------------EEELLS--EACG-----HRE 66

  Fly   138 LQKRIIGGRPAQFAEYPWQAHIRI-AEYQCGGVLISANMVATAAHCIQQAHL-ADITVYLGELDT 200
            :...:.||..:....:||||.:|: ..::|||.|:|...|.:||||.|:.:. ::.||.||||.:
Human    67 IHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTS 131

  Fly   201 QDLGHIHEPLPVEKHGVLQKIIHPRFNFR-----------MTQPD-----RYDIALLKLAQPTSF 249
            :       |.|              :|.|           :..||     |.|||||:||...::
Human   132 R-------PTP--------------WNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTY 175

  Fly   250 TEHILPICLPQYPIRLIGRKGL-IAGWGKTEAHMGHAGTNM-----LQVASVPIITTLDCIRWHE 308
            ..:|.|||:.......:.|... :.|||.    :..:||.:     |:.|.|.|:....|....|
Human   176 NAYIQPICIESSTFNFVHRPDCWVTGWGL----ISPSGTPLPPPYNLREAQVTILNNTRCNYLFE 236

  Fly   309 SKQINVEIKAEMFCAGHSDGHMDACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNV 373
            .......|...|||||..||.:|.|.||||||||..:.|.:..|||.|.|..||..::||:|.|:
Human   237 QPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNI 301

  Fly   374 QKTVRWIQEVVARNEP 389
            .....||:.|::.:.|
Human   302 SVYFHWIRRVMSHSTP 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	84/262 (32%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	86/264 (33%)
PRSS41	NP_001382429.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4261
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960