DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and tmprss4b

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	256	Identity:	91/256 - (35%)
Similarity:	135/256 - (52%)	Gaps:	30/256 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 QKRIIGGRPAQFAEYPWQAHIRI-AEYQCGGVLISANMVATAAHCI--QQAHLADITVYLGELDT 200
            :.||:||.......:|||..::. ..:.|||.|:|.:.:.:||||.  :...|:..||.||:...
Zfish   199 EDRIVGGVETSIEHWPWQVSLQFNHRHMCGGSLLSTSWIISAAHCFTGRTQELSRWTVVLGQTKV 263

  Fly   201 QDLGHIHEPLPVEKHGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRL 265
            .|:..:         .|...:||..:| |:|  :.:|||:|||..|....|.|||:|||.:.:.:
Zfish   264 MDVVGV---------SVDMIVIHKDYN-RLT--NDFDIAMLKLTWPVKTGESILPVCLPPHQLAI 316

  Fly   266 IGRKGL--IAGWGKTEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQ--INVEIKAEMFCAGHS 326
               |.:  :.|||..:.  |.|...:||.||||::...:|     ||.  .:..|...|.|||..
Zfish   317 ---KDMLVVTGWGLLKE--GGALPTVLQKASVPLVNRSEC-----SKPTIYSSSITPRMLCAGFL 371

  Fly   327 DGHMDACLGDSGGPLVIKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEVVARN 387
            .|::|||.||||||||... .|:.|:||.|.|.||..:.:||:|.:|.:.:.||..|:.||
Zfish   372 QGNVDACQGDSGGPLVYLS-SRWQLIGIVSWGVGCAREGKPGVYADVTQLLDWIYTVMERN 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	86/245 (35%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	87/247 (35%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	86/245 (35%)
		Tryp_SPc	202..427	CDD:238113	87/247 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910