DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13744 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_610439.1	Gene:	CG13744 / 35906	FlyBaseID:	FBgn0033363	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	428	Identity:	119/428 - (27%)
Similarity:	180/428 - (42%)	Gaps:	84/428 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLLWLCLCLLLLI----CQSSPSQA----------NILNTLLGVPAECVHQSGVWPCKL---SFS 50
            ||:.|.:.|:||.    .||....|          .....|...|...|...||..||:   ...
Mouse   155 LLISLVISLILLYGGRETQSPRGTAVYFWRGHTGIKYKEPLESCPIHAVRCDGVVDCKMKSDELG 219

  Fly    51 C----WLQGGKHAKGCGSNKWLFSCCVA----ETQHPHQQ------------QHHSPSSPLANLV 95
            |    |.:.........|.:||..|..:    :::...||            .|...:|... |.
Mouse   220 CVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTTEVAHRDITSSFL-LS 283

  Fly    96 DYG---KLKLNLNSLPKRIMLRRRDDNELLNPKPECGVPRTAQNTLQKRIIGGRPAQFAEYPWQA 157
            :|.   :..|..:..|.|..:..:..:        ||:     ..:..||:||.....:::|||.
Mouse   284 EYNTTIQESLYRSQCPSRRYVSLQCSH--------CGL-----RAMTGRIVGGALTSESKWPWQV 335

  Fly   158 HIRI-AEYQCGGVLISANMVATAAHCI---QQAHLADITVYLGELDTQDLGHIHEPLPVEKHGVL 218
            .:.. ..:.|||.||.|..|.|||||.   ::..|....||.|      ..::|: || |...:.
Mouse   336 SLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKLLEGWKVYAG------TSNLHQ-LP-EAASIS 392

  Fly   219 QKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLIGRK-GL-----IAGWGK 277
            |.||:..:.   .:.|.|||||::|::|.:.:.||.|.|||.:     |:. ||     |.|:||
Mouse   393 QIIINGNYT---DEQDDYDIALIRLSKPLTLSAHIHPACLPMH-----GQTFGLNETCWITGFGK 449

  Fly   278 TEAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMFCAGHSDGHMDACLGDSGGPLV 342
            |: ......:..|:...|.:|....|   ::....:..:...|.|||...|..|:|.||||||||
Mouse   450 TK-ETDEKTSPFLREVQVNLIDFKKC---NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLV 510

  Fly   343 IKERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWI 380
            .::..|:.|.|:||.|.|||..::||:|..|.:.:.||
Mouse   511 CEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	141..380	CDD:214473	84/248 (34%)
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	85/249 (34%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060	4/15 (27%)
		SRCR_2	225..314	CDD:373897	16/102 (16%)
		Tryp_SPc	319..548	CDD:214473	84/248 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000