Protein Alignment CG13744 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_610439.1
• Gene: CG13744 / 35906
• FlyBaseID: FBgn0033363
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 94/299 - (31%)
• Similarity: 145/299 - (48%)
• Gaps: 45/299 - (15%)

  Fly   100 LKLNL---NSLPKRIMLRR--RDDNELLNPKPECGVPRTAQNTL--QKRIIGGRPAQFAEYPWQA 157
            ||.|:   |::|..|.|..  :..:|:|.... ||  |...|::  ..:|:.|:.:....:||||
Human   139 LKNNMASWNAVPASIKLMEISKAASEMLTNNC-CG--RQVANSIITGNKIVNGKSSLEGAWPWQA 200

  Fly   158 HIR-IAEYQCGGVLISANMVATAAHCI-QQAHLADITVYLGELDTQDLGHIHEPLPVEKHGVLQK 220
            .:: ...:.||..|||:..:.:||||. ::.:..|.||..|.:       :::|....|   :|.
Human   201 SMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIV-------VNKPYMTRK---VQN 255

  Fly   221 IIHPRFNFRMTQPDRY-DIALLKLAQPTSFTEHILPICLPQYPIRLIGRKG-LIAGWGKTEAHMG 283
            ||   |:...:.|..: ||||::||:..||||:|..||||:..::|..... ::.|||
Human   256 II---FHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWG------- 310

  Fly   284 HAGTNMLQVASVPIITTLDCIRWHESKQINVE------IKAEMFCAGHSDGHMDACLGDSGGPLV 342
                .:....|.|:|...|.::..::|..|..      :...|.|||...|..|||..||||||.
Human   311 ----TLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLA 371

  Fly   343 IKE-RGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWI 380
            ..: |..:.||||.|.|.|||..::||:|..|.....||
Human   372 YPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	81/250 (32%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188	2/2 (100%)
		Tryp_SPc	185..413	CDD:238113	81/250 (32%)