Protein Alignment CG13744 and PRSS21

DIOPT Version :10

• Sequence 1: NP_610439.1
• Gene: CG13744 / 35906
• FlyBaseID: FBgn0033363
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 94/304 - (30%)
• Similarity: 142/304 - (46%)
• Gaps: 34/304 - (11%)

  Fly    98 GKLKLNLNSLPKRIMLRRRDDNELLNPKPECGVPRTAQNTLQKRIIGGRPAQFAEYPWQAHIRIA 162
            |.|.|.|  |..|..||:.:..|.......||     :..:..||:||..|:...:|||..:|:.
Human     5 GALLLAL--LLARAGLRKPESQEAAPLSGPCG-----RRVITSRIVGGEDAELGRWPWQGSLRLW 62

  Fly   163 E-YQCGGVLISANMVATAAHCIQ-QAHLADIT---VYLGELDTQDLGHIHEPLP--------VEK 214
            : :.||..|:|.....|||||.: .:.|:|.:   |..|:|.:         :|        ..:
Human    63 DSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTS---------MPSFWSLQAYYTR 118

  Fly   215 HGVLQKIIHPRFNFRMTQPDRYDIALLKLAQPTSFTEHILPICLPQYPIRLIGRKGL-IAGWGKT 278
            :.|....:.||:    .....|||||:||:.|.::|:||.||||.........|... :.|||..
Human   119 YFVSNIYLSPRY----LGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYI 179

  Fly   279 EAHMGHAGTNMLQVASVPIITTLDCIRWHESKQINVEIKAEMFCAGHSDGHMDACLGDSGGPLVI 343
            :........:.||...|.||....|...........:|..:|.|||::.|..|||.|||||||..
Human   180 KEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC 244

  Fly   344 KERGRFVLVGITSAGFGCGVDHQPGIYHNVQKTVRWIQEVVARN 387
            .:.|.:..:|:.|.|.|||..::||:|.|:.....|||:::|::
Human   245 NKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLMAQS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13744	NP_610439.1	Tryp_SPc	142..383	CDD:238113	81/254 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	80/253 (32%)