DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	361	Identity:	110/361 - (30%)
Similarity:	165/361 - (45%)	Gaps:	56/361 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 SSSLNSW-----EHETGGHLGSISGITNH-LDSFFDAESQAPLDS--------AGAPPP---HEP 263
            |.|.|:|     |..|..|..:...:..: :...|.:.:..||.|        .|...|   ...
Zfish   130 SPSDNTWKSVCSESFTQQHAETACQLLGYSVSPVFSSIAVGPLPSDLKISFCMVGTTKPQTFQSA 194

  Fly   264 LPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHP 328
            :.:.:..:.|.|:.|:.  :||                    || :....:|||||......:.|
Zfish   195 VSDRKVCSTGTVISLSC--SAD--------------------CG-LSRNQDRIVGGKDADIANWP 236

  Fly   329 WQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVRGQEERLNH--EEY 391
            |||:|..||    :.:|||:|::..||:|||||.    |.:.:..|..|.|......|:.  ..|
Zfish   237 WQVSLQYSG----QHTCGGSLVTPNWVVTAAHCF----NGDGRKALSRWTVVSGITYLSSTPSSY 293

  Fly   392 GIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLT-GKMATVAGWGRTRHGQ 455
             ::...|:.:|.||:...|:.:|:|...:...:...||||||....|. |....|.|||......
Zfish   294 -VKEIIVNSNYKPAESDFDITMIKLQSPITLSESRRPVCLPPQNLGLKGGDGLVVTGWGHMAEKG 357

  Fly   456 STVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGR 520
            .::.|:||:..::||.:.:|.   .......:|....:|||...||.|:|||||||||....| |
Zfish   358 GSLSSMLQKAQIQVIDSAQCS---SPTVYGSSITPRMICAGVMAGGVDACQGDSGGPLVHLAD-R 418

  Fly   521 KTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVM 556
            ..|:|:||||:||.|...||||||:.:.:.|.:.||
Zfish   419 WVLVGVVSWGVGCARPGFPGVYTNVDQMLDWAHSVM 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	87/239 (36%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	87/241 (36%)
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335	20/110 (18%)
		Tryp_SPc	223..449	CDD:214473	87/238 (37%)
		Tryp_SPc	224..449	CDD:238113	86/237 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910