Protein Alignment CG8172 and Tmprss6

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_082178.2
• Gene: Tmprss6 / 71753
• MGIID: 1919003
• Length: 811
• Species: Mus musculus
• Alignment Length: 273
• Identity: 106/273 - (38%)
• Similarity: 144/273 - (52%)
• Gaps: 22/273 - (8%)

  Fly   291 GSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWV 355
            |.....|.|......|| :...|:|||||..:..|..|||.:|...|    :..||||||::|||
Mouse   553 GQSDCRDGSDEQHCDCG-LQGLSSRIVGGTVSSEGEWPWQASLQIRG----RHICGGALIADRWV 612

  Fly   356 ITAAHCVASTPNSNMKIRLGEWDVRGQEERLNHE-----EYGIERKEVHPHYNPADFVNDVALIR 415
            ||||||......::.|:    |.|...:.|.|..     .:.:.|..:||::.......||||::
Mouse   613 ITAAHCFQEDSMASPKL----WTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQ 673

  Fly   416 LDRNVVYKQHIIPVCLPPSTTKL-TGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWF 479
            ||..|||...:.|||||..:... .|:...:.|||..|.| ..|.:.||:|||:::..|.|...:
Mouse   674 LDHPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREG-GPVSNTLQKVDVQLVPQDLCSEAY 737

  Fly   480 RAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTL-TMDGRKTLIGLVSWGIGCGREHLPGVYT 543
                 |..:....|||||:.|.:|:|||||||||.. ...||..|.||||||:||||.:..||||
Mouse   738 -----RYQVSPRMLCAGYRKGKKDACQGDSGGPLVCREPSGRWFLAGLVSWGLGCGRPNFFGVYT 797

  Fly   544 NIQRFVPWINKVM 556
            .:.|.:.||.:|:
Mouse   798 RVTRVINWIQQVL 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	98/245 (40%)
Tmprss6	NP_082178.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		SEA	88..182	CDD:460188
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:395011	3/12 (25%)
		Tryp_SPc	577..809	CDD:238113	98/245 (40%)