Protein Alignment CG8172 and PRSS56

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 104/274 - (37%)
• Similarity: 134/274 - (48%)
• Gaps: 37/274 - (13%)

  Fly   302 PVPG-CGE-------VYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITA 358
            |.|| |||       |.....|||||.:...|:.||.|.|...|    :..|||.|::..||:||
Human    83 PEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGG----QPLCGGVLVAASWVLTA 143

  Fly   359 AHCVASTPNSNMKIRLGEWDV------RGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLD 417
            |||....||..:      |.|      ||::.    ||..:.|...||.::|..|.||:||::|.
Human   144 AHCFVGAPNELL------WTVTLAEGSRGEQA----EEVPVNRILPHPKFDPRTFHNDLALVQLW 198

  Fly   418 RNVVYKQHIIPVCLPPSTTK-LTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRA 481
            ..|.......|||||....: ..|....:||||..........:| :|..|.::|.|.|:|.. .
Human   199 TPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV-REARVPLLSTDTCRRAL-G 261

  Fly   482 AGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDG---RKTLIGLVSWGIGCGREHLPGVYT 543
            .|.|.:   ..|||||..||.||||||||||||.:..|   |:.|.|:.|||.|||....|||||
Human   262 PGLRPS---TMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYT 323

  Fly   544 NIQRFVPWINKVMA 557
            .:..|..|:.:.|:
Human   324 RVAVFKDWLQEQMS 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	95/248 (38%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	95/248 (38%)
		PksD	<178..600	CDD:442550	66/165 (40%)