Protein Alignment CG8172 and PRSS22

DIOPT Version :9

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_071402.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 317
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 94/267 - (35%)
• Similarity: 148/267 - (55%)
• Gaps: 15/267 - (5%)

  Fly   297 DASYRPV-PGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAH 360
            :|:..|| |.||:. .:.||:|||..:.....||.|::.|:|    ...|.|:|:::||||||||
Human    31 NAARIPVPPACGKP-QQLNRVVGGEDSTDSEWPWIVSIQKNG----THHCAGSLLTSRWVITAAH 90

  Fly   361 CVASTPNSN--MKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYN-PADFVNDVALIRLDRNVVY 422
            |.....|..  ..:.||.|.:.....|  .::.|:...|.||.|: ......|:||:||:|::.:
Human    91 CFKDNLNKPYLFSVLLGAWQLGNPGSR--SQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQF 153

  Fly   423 KQHIIPVCLPPSTTKL-TGKMATVAGWGRTRHGQSTV-PSVLQEVDVEVISNDRCQR-WFRAAGR 484
            .:.::|:|||.::..| ......::|||..:.|.... |..||::.|.:|.::.|.. ::|.||:
Human   154 SERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQ 218

  Fly   485 REAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFV 549
            .....|: |||||.:|.||:|.|||||||...:||...|.|::|||.||...:.||||.::....
Human   219 GPITEDM-LCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHR 282

  Fly   550 PWINKVM 556
            .|:.|::
Human   283 SWVEKIV 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	85/242 (35%)
		Tryp_SPc	316..555	CDD:238113	85/244 (35%)
PRSS22	NP_071402.1	Tryp_SPc	50..288	CDD:238113	85/244 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12542
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4849
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.890