Protein Alignment CG8172 and PRSS2

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 91/257 - (35%)
• Similarity: 133/257 - (51%)
• Gaps: 33/257 - (12%)

  Fly   314 NRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNM-------- 370
            ::||||:.....|.|:||:| .||:    ..|||:|||.:||::|.||..|..||.:
Human    22 DKIVGGYICEENSVPYQVSL-NSGY----HFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYH 81

  Fly   371 --KIRLGEWDV---RGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVC 430
              ::||||.::   .|.|:.:|..:  |.|   ||.||.....||:.||:|....|....:..:.
Human    82 RIQVRLGEHNIEVLEGNEQFINAAK--IIR---HPKYNSRTLDNDILLIKLSSPAVINSRVSAIS 141

  Fly   431 LPPSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCA 495
            | |:.....|..:.::|||.|....:..|..||.:|..|:|...|:     |.....|.:...|.
Human   142 L-PTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECE-----ASYPGKITNNMFCV 200

  Fly   496 GYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMA 557
            |:.:||:||||||||||:.    ....|.|:||||.||.:::.|||||.:..:|.||...:|
Human   201 GFLEGGKDSCQGDSGGPVV----SNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	90/251 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	90/251 (36%)