DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and tmprss13a

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001152984.1	Gene:	tmprss13a / 559754	ZFINID:	ZDB-GENE-090309-3	Length:	506	Species:	Danio rerio

Alignment Length:	461	Identity:	130/461 - (28%)
Similarity:	183/461 - (39%)	Gaps:	90/461 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 CVDKDLDAEESPHAAPVNNTSDIIHLHDIYPDLSTNANKPQHHLHHHSGNGLSAAPSTSSTASSS 175
            |::.|..:||| |   .....|.|.:...|...|...:..||:.|     |:.........|...
Zfish   122 CMEDDCSSEES-H---FEGAHDGIKVPPTYSSSSLLCDGVQHYQH-----GIDEMDCVRFGAGGE 177

  Fly   176 ARPAYPSSYYGTKRPTHYSGSNPYKPGSSAGGSSRPSSSSSSSLNSWEHE------TGGHLGSIS 234
            .:  ..:::.|...|..|.|.|...............|..||:|||...|      |.|.|  |.
Zfish   178 LQ--LKTAHNGQFLPVCYEGWNISYADQICEQLGFRRSYESSALNSKSSEALILEPTSGLL--IQ 238

  Fly   235 GITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDAS 299
            |:.|......|.:|                           :.|...:
Zfish   239 GLANVSSGCLDDKS---------------------------VSLQCSD----------------- 259

  Fly   300 YRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCV-A 363
                  ||:..: |:||:||.::..|.:||||:|    ...:...|||.|||..::::||||. .
Zfish   260 ------CGKQQS-SSRIIGGTTSELGQYPWQVSL----HYNKAHVCGGTLISPDFIVSAAHCFQG 313

  Fly   364 STPNSNMKIRLGEWDVR---GQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQH 425
            ...||      ..|.|.   ..::.|. ..|.:::..|...||.....|||||:.|.|.|.:...
Zfish   314 KMANS------AYWLVYVGIVSQQSLG-MPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYT 371

  Fly   426 IIPVCLPPSTTKLTGKM-ATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIH 489
            ..|||||......:|.: ...:|:|.|:.|.....|.|..|.|.:|.:..|.......|   .|.
Zfish   372 TQPVCLPTFNQTFSGGLQCWTSGFGTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCG---LIT 433

  Fly   490 DVFLCAGYKDGGRDSCQGDSGGPLTLTMD-GRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWIN 553
            :..:|||...||||||||||||||....| .|..|:|:.|||.|||::..||||:.:..|:|||.
Zfish   434 NNMICAGDLKGGRDSCQGDSGGPLVCKDDNNRWYLVGITSWGAGCGQKQKPGVYSRVTSFLPWIY 498

  Fly   554 KVMAND 559
            ..|..:
Zfish   499 TKMQQE 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	88/242 (36%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	89/244 (36%)
tmprss13a	NP_001152984.1	SRCR_2	178..261	CDD:295335	21/136 (15%)
		Tryp_SPc	268..497	CDD:214473	88/242 (36%)
		Tryp_SPc	269..497	CDD:238113	87/241 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910