Protein Alignment CG8172 and Tmprss2

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_056590.2
• Gene: Tmprss2 / 50528
• MGIID: 1354381
• Length: 490
• Species: Mus musculus
• Alignment Length: 339
• Identity: 105/339 - (30%)
• Similarity: 146/339 - (43%)
• Gaps: 27/339 - (7%)

  Fly   220 NSWEHETGGHLGSISGITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAA 284
            :.|....|.......|..|:..|     ||...|.:|          |.:|...||...|.....
Mouse   173 DDWSESYGRAACKDMGYKNNFYS-----SQGIPDQSG----------ATSFMKLNVSSGNVDLYK 222

  Fly   285 DEYQSGGSGGYHDASYRPVPGCG-EVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGA 348
            ..|.|.........|.|.:. || ....|.:|||||.:...|..||||:|...|...    |||:
Mouse   223 KLYHSDSCSSRMVVSLRCIE-CGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHV----CGGS 282

  Fly   349 LISNRWVITAAHCVASTPNSNMKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYNPADFVNDVAL 413
            :|:..|::|||||| ..|.|:.:.......:..|........:.:|:...||:|:.....||:||
Mouse   283 IITPEWIVTAAHCV-EEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIAL 346

  Fly   414 IRLDRNVVYKQHIIPVCLP-PSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQR 477
            ::|...:.:...:.||||| |.......:...::|||.| :.:.....||....|.:|...:|..
Mouse   347 MKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGAT-YEKGKTSDVLNAAMVPLIEPSKCNS 410

  Fly   478 WFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVY 542
            .:.   ....|....:|||:..|..|||||||||||....:|...|||..|||.||.:...||||
Mouse   411 KYI---YNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVY 472

  Fly   543 TNIQRFVPWINKVM 556
            .|:..|..||.:.|
Mouse   473 GNVTVFTDWIYQQM 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	82/239 (34%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:464747	20/89 (22%)
		Tryp_SPc	254..485	CDD:238113	82/239 (34%)