Protein Alignment CG8172 and ACR

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 103/321 - (32%)
• Similarity: 151/321 - (47%)
• Gaps: 55/321 - (17%)

  Fly   262 EPLPNA--QAFAVGNVLDLNA---GEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHS 321
            |.||.|  ...||..|...||   |.....::....||.                   |||||.:
Human     3 EMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGV-------------------RIVGGKA 48

  Fly   322 TGFGSHPWQVAL-IKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWD-VRGQEE 384
            ...|:.||.|:| |.:....|..:|||:|:::|||:|||||.....|      :.:|. |.|.:|
Human    49 AQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNN------VHDWRLVFGAKE 107

  Fly   385 ---------RLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLT- 439
                     :...:|..:|:..:|..||.|...||:||:.:...:...:.|.|.|||.....|.
Human   108 ITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPR 172

  Fly   440 -GKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQ--RWFRAAGRREAIHDVFLCAGYKDGG 501
             .:...|||||..........|:|.|..|::|..|.|.  :|:.  ||   :....:||||..|.
Human   173 GSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYN--GR---VQPTNVCAGYPVGK 232

  Fly   502 RDSCQGDSGGPLTLTMDGRKT---LIGLVSWGIGCGREHLPGVYTNIQRFVPWI-NKVMAN 558
            .|:||||||||| :..|.:::   ::|:.|||:||.|...||:||....::.|| :|:.:|
Human   233 IDTCQGDSGGPL-MCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	88/257 (34%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	87/254 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421