Protein Alignment CG8172 and KLK12

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 89/239 - (37%)
• Similarity: 123/239 - (51%)
• Gaps: 33/239 - (13%)

  Fly   315 RIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDV 379
            :|..|...|..|.||||.|    |....|.|||.||.:|||:|||||    ..|...:||||..:
Human    21 KIFNGTECGRNSQPWQVGL----FEGTSLRCGGVLIDHRWVLTAAHC----SGSRYWVRLGEHSL 77

  Fly   380 RGQE--ERLNHEEYGIERKEVHPHYNPA--DFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTG 440
            ...:  |::.|..:.:    .||.|..|  ...:|:.|:||...|.....:.|:.| |:.....|
Human    78 SQLDWTEQIRHSGFSV----THPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPL-PNDCATAG 137

  Fly   441 KMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDG--GRD 503
            ....|:|||.|.|.::..|.:||.:::.::|:..|...:  .||   |....:|||   |  |:|
Human   138 TECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVY--PGR---ITSNMVCAG---GVPGQD 194

  Fly   504 SCQGDSGGPLTLTMDGRKTLIGLVSWG-IG-CGREHLPGVYTNI 545
            :|||||||||..    ...|.|||||| :| ||::.:|||||.|
Human   195 ACQGDSGGPLVC----GGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	89/238 (37%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	89/238 (37%)