Protein Alignment CG8172 and Sb

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 758
• Identity: 205/758 - (27%)
• Similarity: 294/758 - (38%)
• Gaps: 255/758 - (33%)

  Fly    15 LVVLCALICLSAPRRA-----------DALGYP-----SAQQEHDMLILDALSRRSGTGYY---- 59
            ||.|..:.||:....|           .:||.|     |::.:.||          .:|:|
  Fly    60 LVALIVVNCLATAAAALITPPDSLESLGSLGIPSSSASSSEDDDDM----------SSGFYRIPH 114

  Fly    60 -------------GENSVMEMLSRMIPQSCRFRGHKFECGLSISCVLGGGKPLDLC-SGGMIWSC 110
                         |:|      .::.|:.|.|...:..|.....|:...||.:.:| ...|..||
  Fly   115 RLEGYPQLQQLQRGQN------FKISPKPCSFGRVEGTCMFVWECIKSEGKHVGMCVDSFMFGSC 173

  Fly   111 CV-------------------DKDLDAEESPHAAP----VNNTSDIIHLHDIYPDLSTNANKPQH 152
            |.                   .|.|.....|.|||    ::..:.|...|    ...|...:|..
  Fly   174 CTHNYTDNIVLPQTAFSYTRPTKPLTLRPRPPAAPYKPMISGMTTIERPH----GAGTLVIRPSG 234

  Fly   153 HLHHHSG--------------------NGLSAAPSTSSTASSS---------------------- 175
              .||.|                    :|.::.||:||::|||
  Fly   235 --PHHQGTLARPHPPPYQSKPTTASDLHGSASHPSSSSSSSSSSNPNSIWHTSTQQQQQQQHQQN 297

  Fly   176 ---------------------------------ARPAYPSSYYGTKRPTHYSGSNP----YKPGS 203
                                             |||:.||.  .||:|..|..:.|    ..|.:
  Fly   298 QQNHWQMTTEPSFITKPRPTGWTKPGIVNLPMPARPSKPSK--PTKKPIVYDRTPPPPPSVPPST 360

  Fly   204 SAGGSS------------------RP-----SSSSSSSLNSWEHETGGHLGSISGITN------- 238
            |...:|                  ||     :|.::||.:.|...|.....|.:..|.
  Fly   361 STSTTSTSLIWPAQTHPPQPHRPTRPQLSPGTSLAASSSSHWPSSTTSTTSSTTSTTTTTTTTRR 425

  Fly   239 --------------------HLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLD------ 277
                                ...:...:.|.....|:..|....|:.::.:.:.|.|..
  Fly   426 TTTPTTTTRRTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQRPTQ 490

  Fly   278 --------LNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRS---------------NRIVGG 319
                    ..:|...:|..        |:|.......|.|.|.|               .|||||
  Fly   491 PTHRTPVLATSGIETNEIS--------DSSIPDAGALGHVKTISAARSECGVPTLARPETRIVGG 547

  Fly   320 HSTGFGSHPWQVALIKSGFL----TRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVR 380
            .|..||..||||::.::.|.    |.:  ||||||:..|:.||.|||.....|.::||:||:|..
  Fly   548 KSAAFGRWPWQVSVRRTSFFGFSSTHR--CGGALINENWIATAGHCVDDLLISQIRIRVGEYDFS 610

  Fly   381 GQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMATV 445
            ..:|:|.:.|.|:.:|.|||.|:...:..|:||::|::.:.:..|:.|:|||.:.:.|.|..|||
  Fly   611 HVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDSLLIGMNATV 675

  Fly   446 AGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSG 510
            .||||...| .|:|||||||.|.::|||.|:..|..|||:|.|.|:||||||:.||:||||||||
  Fly   676 TGWGRLSEG-GTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSG 739

  Fly   511 GPL-TLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWI 552
            ||| ..:.|||..|.|::||||||...:||||.|.|.:|.|||
  Fly   740 GPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	119/242 (49%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	119/242 (49%)