DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and ea

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	112/299 - (37%)
Similarity:	150/299 - (50%)	Gaps:	61/299 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 SYRPVPG-CGEVYTRSNRIVGGHSTGFGSHPWQVALI-------KSGFLTRKLSCGGALISNRWV 355
            |..|:|| ||.:.  ||||.||..|.....|| :|||       |.|.     .|||:|||.|:|
  Fly   112 SLLPLPGQCGNIL--SNRIYGGMKTKIDEFPW-MALIEYTKSQGKKGH-----HCGGSLISTRYV 168

  Fly   356 ITAAHCVASTPNSNMK----------IRLGEW----------DVRGQEE-RLNHEEYGIERKEVH 399
            |||:|||      |.|          :|||||          ||||.:: ...|.:..:||...|
  Fly   169 ITASHCV------NGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPH 227

  Fly   400 PHYNPA--DFVNDVALIRLDRNVVYKQHIIPVCLPPS----TTKLTGKMATVAGWGRTRHGQSTV 458
            |.|.||  :.|||:||:||.:.|.|...:.|:|||..    :....|....|||||:|.  |.:.
  Fly   228 PDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTE--QLSA 290

  Fly   459 PSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKT- 522
            .::..:..||....|.||..:  :.:...:.|..:|||.|: |.|||:||||||| :.:|..|.
  Fly   291 SNLKLKAAVEGFRMDECQNVY--SSQDILLEDTQMCAGGKE-GVDSCRGDSGGPL-IGLDTNKVN 351

  Fly   523 ----LIGLVSWG-IGCGREHLPGVYTNIQRFVPWINKVM 556
                |.|:||:| ..||....|||||.:.::|.||...:
  Fly   352 TYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	102/276 (37%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	103/278 (37%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	102/276 (37%)
		Tryp_SPc	128..389	CDD:238113	103/278 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457506
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.840