Protein Alignment CG8172 and KLKB1

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 102/309 - (33%)
• Similarity: 157/309 - (50%)
• Gaps: 55/309 - (17%)

  Fly   276 LDLNAGEAADEYQSGGSGGYHDASYRPV-PGCGEVYT--RSNRIVGGHSTGFGSHPWQVALIKSG 337
            |.::.......|.:.||.||   |.|.. .|...|.|  .|.|||||.::.:|..||||:|....
Human   362 LSMDGSPTRIAYGTQGSSGY---SLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL 423

  Fly   338 FLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVRGQEERLNHEEYGI--------- 393
            ...|.| |||:||.::||:|||||....|..::      |.:..          ||
Human   424 TAQRHL-CGGSLIGHQWVLTAAHCFDGLPLQDV------WRIYS----------GILNLSDITKD 471

  Fly   394 ----ERKE--VHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMAT------VA 446
                :.||  :|.:|..::..:|:|||:|...:.|.:...|:|||..     |..:|      |.
Human   472 TPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK-----GDTSTIYTNCWVT 531

  Fly   447 GWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGG 511
            |||.::. :..:.::||:|::.:::|:.||:.:    :...|....:|||||:||:|:|:|||||
Human   532 GWGFSKE-KGEIQNILQKVNIPLVTNEECQKRY----QDYKITQRMVCAGYKEGGKDACKGDSGG 591

  Fly   512 PLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWI-NKVMAND 559
            ||....:|...|:|:.|||.||.|...|||||.:..::.|| .|..::|
Human   592 PLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSD 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	87/260 (33%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519	8/26 (31%)
		Tryp_SPc	402..632	CDD:238113	85/256 (33%)