Protein Alignment CG8172 and KLK2

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 87/271 - (32%)
• Similarity: 120/271 - (44%)
• Gaps: 43/271 - (15%)

  Fly   305 GC-GEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNS 368
            || |.|....:|||||......|.|||||:...|:    ..|||.|:..:||:|||||:    ..
Human    13 GCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGW----AHCGGVLVHPQWVLTAAHCL----KK 69

  Fly   369 NMKIRLG-----EWDVRGQEERLNHEEYGIERKEVHPHYNPA-----------DFVNDVALIRLD 417
            |.::.||     |.:..||...::|       ...||.||.:           |..:|:.|:||.
Human    70 NSQVWLGRHNLFEPEDTGQRVPVSH-------SFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLS 127

  Fly   418 RNVVYKQHIIPVCLPPSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAA 482
            ....... ::.|...|:.....|.....:|||.....:...|..||.|.:.::|||.|.|.:
Human   128 EPAKITD-VVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY--- 188

  Fly   483 GRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWG-IGCGREHLPGVYTNIQ 546
              .|.:.:..||||...||:|:|.|||||||..    ...|.|:.||| ..|.....|.|||.:.
Human   189 --SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC----NGVLQGITSWGPEPCALPEKPAVYTKVV 247

  Fly   547 RFVPWINKVMA 557
            .:..||...:|
Human   248 HYRKWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	81/255 (32%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	81/255 (32%)