DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	386	Identity:	111/386 - (28%)
Similarity:	167/386 - (43%)	Gaps:	70/386 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 PYKPGSSAGGSSRPSSSS--SSSLNSWEHETGGHLGSISGITNHLDSFFDAES-----QAPLDSA 255
            |.|||.:...|...|:..  .::..:|        .|:.     .|:|.:|.:     |...:|.
  Rat   138 PEKPGVTVRLSKDRSTLQVLDAARGTW--------ASVC-----FDNFTEALAKTACRQMGYNSQ 189

  Fly   256 GAPPPHEPLPNAQAFAV----GNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRI 316
            .|..|.|..|| |...|    ||..:|.....:....||..     .|.|.: .||: ..::.|:
  Rat   190 PAFGPVEMGPN-QTLLVTPVTGNSQELQMQNGSRSCLSGSL-----VSLRCL-DCGK-SLKTTRV 246

  Fly   317 VGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVRG 381
            |||......|.||||::    ...::..|||:::.:.|::|||||.      ...:.:..|.||.
  Rat   247 VGGVEASADSWPWQVSI----QYNKQHVCGGSILDHHWILTAAHCF------RKYLDVSSWKVRA 301

  Fly   382 QEERLNH------------EEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPS 434
            ...:|.:            |...::.||           .|:||::|...:.:...:.|:|||.|
  Rat   302 GSNKLGNSPSLPVAKIFIAEPNPLQPKE-----------KDIALVKLKMPLTFSGSVRPICLPFS 355

  Fly   435 TTKLTGKMAT-VAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYK 498
            ..:|...|.. |.|||.|......:...|.:..|:||.:.||.......|...|   ..||||..
  Rat   356 DEELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTA---GMLCAGTP 417

  Fly   499 DGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMAND 559
            .||:|:|||||||||....| :..::|:||||.|||....|||||.:..::.||..|..::
  Rat   418 QGGKDTCQGDSGGPLMYHYD-KWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNVRRSE 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	79/249 (32%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	80/251 (32%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	22/108 (20%)
		Tryp_SPc	245..470	CDD:214473	79/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910