DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and PRSS41

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_001382429.1	Gene:	PRSS41 / 360226	HGNCID:	30715	Length:	334	Species:	Homo sapiens

Alignment Length:	314	Identity:	105/314 - (33%)
Similarity:	151/314 - (48%)	Gaps:	49/314 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 GNVLDLNAGEAADEYQSGGSGGYH-----DASYRPV--PGCG--EVYTRSNRIVGGHSTGFGSHP 328
            |.:..|.||..|.....||....|     ::....:  ..||  |::.   .:.||..:..|..|
Human    22 GELGALQAGPGAARRPGGGGREGHFLCPAESQEEELLSEACGHREIHA---LVAGGVESARGRWP 83

  Fly   329 WQVALIKSGFLTRKLSCGGALISNRWVITAAHCVAS--TPNSNMKIRLGE-------WDVRGQEE 384
            ||.:|    .|.|:..|||:|:|.|||::||||...  .| |...::|||       |::|....
Human    84 WQASL----RLRRRHRCGGSLLSRRWVLSAAHCFQKHYYP-SEWTVQLGELTSRPTPWNLRAYSS 143

  Fly   385 R-------LNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKM 442
            |       :|.:..|:.|             ||:||:||..:|.|..:|.|:|:..||.....:.
Human   144 RYKVQDIIVNPDALGVLR-------------NDIALLRLASSVTYNAYIQPICIESSTFNFVHRP 195

  Fly   443 -ATVAGWGRTRHGQSTVPSV--LQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDS 504
             ..|.|||......:.:|..  |:|..|.:::|.||...|.....|..|.|...|||.:||..|:
Human   196 DCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDT 260

  Fly   505 CQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMAN 558
            |:|||||||....||....:|:||||:.||:.:.|||||||..:..||.:||::
Human   261 CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSH 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	90/255 (35%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	92/257 (36%)
PRSS41	NP_001382429.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4261
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426785at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.970