Protein Alignment CG8172 and TMPRSS9

DIOPT Version :9

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 148/583 - (25%)
• Similarity: 221/583 - (37%)
• Gaps: 173/583 - (29%)

  Fly     2 LPLPRHSKDTWLRLVVLCALICLSAPRRADALGYPSAQQEHDMLILDALSRRSGTGYYGEN---- 62
            ||..||.:.           :||.|....    :|.:::   .||       ||.||..|:
Human   336 LPFGRHIQP-----------VCLPAATHI----FPPSKK---CLI-------SGWGYLKEDFLVK 375

  Fly    63 ------SVMEMLSRMIPQSCRFRGH----KFEC-----GLSISCVLGGGKPLDLC---SGGMIWS 109
                  :.:|:|.:.:..|  ..||    :..|     |...||....|.|| :|   ||....:
Human   376 PEVLQKATVELLDQALCAS--LYGHSLTDRMVCAGYLDGKVDSCQGDSGGPL-VCEEPSGRFFLA 437

  Fly   110 CCVDKDLDAEESPHAAPVNNTSDIIHLHDIYPDLSTNANKPQHHLHHHSGNGLSAAPSTSSTASS 174
            ..|...:...|:......   :.:..|.|...:.:|.|:.|             .||:.:..
Human   438 GIVSWGIGCAEARRPGVY---ARVTRLRDWILEATTKASMP-------------LAPTMAPA--- 483

  Fly   175 SARPAYPSSYYGTKRPTHYSGSNPYKPGSSAGGSSRPSSSSSSSLNSWEHETGGHLGSISGITNH 239
               ||.||:.:.|         :|..|..|.     |:.|
Human   484 ---PAAPSTAWPT---------SPESPVVST-----PTKS------------------------- 506

  Fly   240 LDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVP 304
                ..|.|..|||....|...|
Human   507 ----MQALSTVPLDWVTVPKLQE------------------------------------------ 525

  Fly   305 GCG--EVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPN 367
             ||  ....:..|:|||.....|..||||:| |.|   .:..||..::.:||:::||||...|..
Human   526 -CGARPAMEKPTRVVGGFGAASGEVPWQVSL-KEG---SRHFCGATVVGDRWLLSAAHCFNHTKV 585

  Fly   368 SNMKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLP 432
            ..::..||...:.|...  :..:.|:.|..:||.|||.....|:|::.|...:.:.::|.|||||
Human   586 EQVRAHLGTASLLGLGG--SPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLP 648

  Fly   433 PSTTKL-TGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAG 496
            .:..|. .|:...::|||.|:.|.:|.|.:||:..|.:|....|...:..     ::.|..:|||
Human   649 LAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNF-----SLTDRMICAG 708

  Fly   497 YKDGGRDSCQGDSGGPLTL-TMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMAN 558
            :.:|..|||||||||||.. ...|...|.|:|||||||.:...|||||.|.|...||.::|::
Human   709 FLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	87/238 (37%)
		Tryp_SPc	316..555	CDD:238113	88/240 (37%)
TMPRSS9	NP_001382442.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810