DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and OVCH2

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	283	Identity:	98/283 - (34%)
Similarity:	152/283 - (53%)	Gaps:	37/283 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PGCGE---------VYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAA 359
            |.||:         .:...:||:||.....||:||||:|.:    .:|..|||:::|.:||||||
Human    35 PSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQ----RQKHICGGSIVSPQWVITAA 95

  Fly   360 HCVASTPN--SNMKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYN---PADFVNDVALIRLDRN 419
            ||:|:. |  |.:.:..||:|:...:.  ..:...||...:|||::   |.|:  |:||:::...
Human    96 HCIANR-NIVSTLNVTAGEYDLSQTDP--GEQTLTIETVIIHPHFSTKKPMDY--DIALLKMAGA 155

  Fly   420 VVYKQHIIPVCLPPSTTKL-TGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAG 483
            ..:...:.|:|||....:. .|.:.|.|||||...| ..:..|||||::.:::.:.|.......
Human   156 FQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEG-GVLSQVLQEVNLPILTWEECVAALLTL- 218

  Fly   484 RREAIHDVFLCAGYKDGGRDSCQGDSGGPLTL-TMDGRKTLIGLVSWGIGCGR----------EH 537
            :|......|||.|:.|||||:|||||||.|.. ...|..||.|:.|||:||||          :.
Human   219 KRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQG 283

  Fly   538 LPGVYTNIQRFVPWINKVMANDN 560
            .||::|:|.:.:|||::.:...|
Human   284 SPGIFTDISKVLPWIHEHIQTGN 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	92/253 (36%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	93/255 (36%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	92/253 (36%)
		Tryp_SPc	56..301	CDD:238113	93/255 (36%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426785at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820