Protein Alignment CG8172 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 92/297 - (30%)
• Similarity: 140/297 - (47%)
• Gaps: 42/297 - (14%)

  Fly   264 LP-NAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSH 327
            || ||.:..| |.:..:.||...:...|         .|.||      ...|||..|......:.
Human   153 LPINASSVQV-NAMSSSTGELTVQASCG---------KRVVP------LNVNRIASGVIAPKAAW 201

  Fly   328 PWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVR-GQEERLNHEEY 391
            |||.:|.....    ..||..||||.|::|||||.....|.:      :|.|. |.:......:.
Human   202 PWQASLQYDNI----HQCGATLISNTWLVTAAHCFQKYKNPH------QWTVSFGTKINPPLMKR 256

  Fly   392 GIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMAT-VAGWGRTRHGQ 455
            .:.|..:|..|..|....|:|::::...|.:...|..:|||.::......:.. :.|:|...:|.
Human   257 NVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPEASASFQPNLTVHITGFGALYYGG 321

  Fly   456 STVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDV---FLCAGYKDGGRDSCQGDSGGPLTLTM 517
            .: .:.|:|..|::||:|.|:: .:..|     :|:   ..||||.:|..|:|:||||||| :|.
Human   322 ES-QNDLREARVKIISDDVCKQ-PQVYG-----NDIKPGMFCAGYMEGIYDACRGDSGGPL-VTR 378

  Fly   518 DGRKT--LIGLVSWGIGCGREHLPGVYTNIQRFVPWI 552
            |.:.|  |||:||||..||::..|||||.:..:..||
Human   379 DLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	78/244 (32%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	78/244 (32%)