DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8172 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	115/365 - (31%)
Similarity:	155/365 - (42%)	Gaps:	77/365 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 PSSSSSSSL--NSWEHETGGHLGSISGITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVG 273
            ||..||..|  ::.|.:..|...||    |||         .|.|...|  .|..:...:....|
  Rat   148 PSYVSSDHLRVDALEEQFQGDFVSI----NHL---------LPDDKVTA--LHHSVYMREGCTSG 197

  Fly   274 NVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGF 338
            :|:.|...                       .||.....|.|||||:.:.....||||:|...|:
  Rat   198 HVVTLKCS-----------------------ACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGY 239

  Fly   339 LTRKLSCGGALISNRWVITAAHCVAST--PNSNMKIRLGEWDVR-GQEERLNH--EEYGIERKEV 398
            ..    |||::|:..|::||||||...  |.|        |.|: |....::.  ..:.:|:...
  Rat   240 HL----CGGSVITPLWIVTAAHCVYDLYHPKS--------WTVQVGLVSLMDSPVPSHLVEKIIY 292

  Fly   399 HPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKL-TGKMATVAGWGRTRHGQSTVPSVL 462
            |..|.|....||:||::|...:.:.:.|.|:|||.|.... .||:...:|||.|..|......||
  Rat   293 HSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGAGDASPVL 357

  Fly   463 QEVDVEVISNDRCQRWFRAAGRREAIHDVF--------LCAGYKDGGRDSCQGDSGGPLTLTMDG 519
            ....|.:|||..|..           .||:        |||||..||.|||||||||||......
  Rat   358 NHAAVPLISNKICNH-----------RDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERR 411

  Fly   520 RKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMAND 559
            ...|:|..|:||||...:.|||||.|..|:.||::.:..|
  Rat   412 LWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERD 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	90/250 (36%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	91/252 (36%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	21/100 (21%)
		Tryp_SPc	216..444	CDD:214473	90/250 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44824
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810