Protein Alignment CG8172 and GZMM

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 74/250 - (29%)
• Similarity: 117/250 - (46%)
• Gaps: 31/250 - (12%)

  Fly   315 RIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLG--EW 377
            :|:||......|.|:..:|.::|    ...|||.|:..:||:|||||:|.. .:.:::.||  ..
Human    25 QIIGGREVIPHSRPYMASLQRNG----SHLCGGVLVHPKWVLTAAHCLAQR-MAQLRLVLGLHTL 84

  Fly   378 DVRGQEERLNHEEYGIERKEVHPHYNPADFV-NDVALIRLDRNVVYKQHIIPVCLPPSTTKL-TG 440
            |..|.       .:.|:....||.|.|...: ||:||::||..|...:.|.|:.||.....: .|
Human    85 DSPGL-------TFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAG 142

  Fly   441 KMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQR---WFRAAGRREAIHDVFLCAGYKDGGR 502
            ...::||||.|..| ..:..||:|:|::|:....|..   |      ..::....:|.......:
Human   143 TRCSMAGWGLTHQG-GRLSRVLRELDLQVLDTRMCNNSRFW------NGSLSPSMVCLAADSKDQ 200

  Fly   503 DSCQGDSGGPLTLTMDGR-KTLIGLVSWGIG-CGREHLPGVYTNIQRFVPWINKV 555
            ..|:|||||||..   |: :.|..::|:... |.....|.|.|.:..:|.||.||
Human   201 APCKGDSGGPLVC---GKGRVLARVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	72/247 (29%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	72/247 (29%)