Protein Alignment CG8172 and GZMK

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 76/260 - (29%)
• Similarity: 113/260 - (43%)
• Gaps: 37/260 - (14%)

  Fly   316 IVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHC-VASTPNSNMKIRLGEWDV 379
            |:||......|.|:..::...|...    |||.||..:||:||||| ...|...:..:.||...:
Human    27 IIGGKEVSPHSRPFMASIQYGGHHV----CGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSL 87

  Fly   380 RGQEERLNHEEYGIERKEVHPH----YNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTG 440
            ...|.    .:..:|.|:..|.    .:|..  ||:.|::|.......:|:..:.:...|:..:|
Human    88 SKNEA----SKQTLEIKKFIPFSRVTSDPQS--NDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSG 146

  Fly   441 KMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRC--QRWFRAAGRREAIHDVFL-----CAGYK 498
            ....|.|||.|..........|:||.|.|:|...|  |.::..        |.|:     |||..
Human   147 TKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNG--------DPFITKDMVCAGDA 203

  Fly   499 DGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNI-QRFVPWI--NKVMANDN 560
            .|.:|||:|||||||..    :.....:||.|..||....||:||.: :::..||  |.|..:.|
Human   204 KGQKDSCKGDSGGPLIC----KGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHTN 264

  Fly   561  560
            Human   265  264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	74/253 (29%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	73/251 (29%)