Protein Alignment CG8172 and Hpn

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: XP_038958886.1
• Gene: Hpn / 29135
• RGDID: 61982
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 152/545 - (27%)
• Similarity: 206/545 - (37%)
• Gaps: 152/545 - (27%)

  Fly    45 LILDALSRRSGTGYYGENSVMEMLSRMIPQSCRFRGHKFECGLSISCV---LGGGKPLDLCSGGM 106
            |:.|....|.|||             .:|.:|              |.   .|.|..|...:||.
  Rat    12 LVQDPSLERQGTG-------------PVPTTC--------------CAEDQAGSGPSLLSVAGGR 49

  Fly   107 IWSCCVDKDLDAEESPHAAPVNNTSDIIHLHDIYPDLSTNANKPQHHLHHHSGNGLSAAPSTSST 171
            ...||        ..|..|.: ....::.|                     :|.|.::....:..
  Rat    50 TAPCC--------SRPKVAAL-TVGTLLFL---------------------TGIGAASWAIVTIL 84

  Fly   172 ASSSARPAYPSSYYGTKRPTHYSGSNPYKPGSS-------AGGSSRPSSSSSSSLNSWEHETGGH 229
            ..|...|.|...               ..||.|       ..|:.|...||.|:
  Rat    85 LRSDQEPLYQVQ---------------LSPGDSRLLVLDKTEGTWRLLCSSRSN----------- 123

  Fly   230 LGSISGITNHLDSFFDAESQAPLD--SAGAP-------PPHEPLPNAQAFA-VGNVLDLNAGEAA 284
             ..::|:......|..|.:.:.||  :|||.       .....||.||... |.:|.|...|...
  Rat   124 -ARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEGGLPLAQRLLDVISVCDCPRGRFL 187

  Fly   285 DEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGAL 349
                   :....|...|.:|        .:|||||..:..|..||||:|...|    ...|||:|
  Rat   188 -------TATCQDCGRRKLP--------VDRIVGGQDSSLGRWPWQVSLRYDG----THLCGGSL 233

  Fly   350 ISNRWVITAAHCVASTPNSNMKIRLGEWDV-RGQEERLNHE--EYGIERKEVHPHYNP------A 405
            :|..||:|||||.   |..|..  |..|.| .|...|.:..  :.|::....|..|.|      .
  Rat   234 LSGDWVLTAAHCF---PERNRV--LSRWRVFAGAVARTSPHAVQLGVQAVIYHGGYLPFRDPTID 293

  Fly   406 DFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLT-GKMATVAGWGRTR-HGQSTVPSVLQEVDVE 468
            :..||:||:.|..::...::|.|||||.:...|. ||:.||.|||.|: :||..|  ||||..|.
  Rat   294 ENSNDIALVHLSSSLPLTEYIQPVCLPAAGQALVDGKVCTVTGWGNTQFYGQQAV--VLQEARVP 356

  Fly   469 VISNDRCQR--WFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLT----LTMDGRKTLIGLV 527
            :|||:.|..  ::   |.:  |.....||||.:||.|:||||||||..    ::...|..|.|:|
  Rat   357 IISNEVCNSPDFY---GNQ--IKPKMFCAGYPEGGIDACQGDSGGPFVCEDRISGTSRWRLCGIV 416

  Fly   528 SWGIGCGREHLPGVYTNIQRFVPWI 552
            |||.||.....|||||.:..|..||
  Rat   417 SWGTGCALARKPGVYTKVIDFREWI 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	100/254 (39%)
Hpn	XP_038958886.1	Hepsin-SRCR	92..200	CDD:462736	27/141 (19%)
		Tryp_SPc	204..441	CDD:238113	98/252 (39%)