Protein Alignment CG8172 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 103/315 - (32%)
• Similarity: 150/315 - (47%)
• Gaps: 50/315 - (15%)

  Fly   258 PPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEV----YTRSNRIVG 318
            |.|.....:.||.||...|           :....||.|      ...||..    ..:.:||:|
Human    33 PSPEPAASSQQAEAVRKRL-----------RRRREGGAH------AEDCGTAPLKDVLQGSRIIG 80

  Fly   319 GHSTGFGSHPWQVAL-IKSGFLTRKLSCGGALISNRWVITAAHCV--ASTPNSNMKIRLGEWDVR 380
            |.....|:.||.|:| ||.|.:...: |||.|:..|||:|||||.  ||.|.....: :|..::.
Human    81 GTEAQAGAWPWVVSLQIKYGRVLVHV-CGGTLVRERWVLTAAHCTKDASDPLMWTAV-IGTNNIH 143

  Fly   381 GQEERLNH-EEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLP-------PSTTK 437
            |   |..| ::..|:...:||::....:|||:||..|.:.|.|..:|.|:|||       ...||
Human   144 G---RYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTK 205

  Fly   438 LTGKMATVAGWGRTR-HGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGG 501
                 ..::|||||: .|.:|  ::||:.:|..||.:.|.......|   .|.:...|||.:||.
Human   206 -----CFISGWGRTKEEGNAT--NILQDAEVHYISREMCNSERSYGG---IIPNTSFCAGDEDGA 260

  Fly   502 RDSCQGDSGGPLTLTMDGRKT--LIGLVSWGIGCGREHLPGVYTNIQRFVPWINK 554
            .|:|:|||||||...:...|.  ::|:.|:|.||||...||||.....:..|:.:
Human   261 FDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	90/253 (36%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		4/12 (33%)
		Tryp_SPc	78..316	CDD:238113	90/253 (36%)