DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and Klkb1

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	98/278 - (35%)
Similarity:	148/278 - (53%)	Gaps:	30/278 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 YQSGGSGGYHDASYR--PVPGCGEVYTRSN-RIVGGHSTGFGSHPWQVAL-IKSGFLTRKLSCGG 347
            |::.||.||   |.|  .|....:..|:.| |||||.::..|..||||:| :|  .:::...|||
  Rat   362 YEAQGSSGY---SLRLCKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVK--LVSQNHMCGG 421

  Fly   348 ALISNRWVITAAHCVASTPNSNMKIRLGEWDVRG----QEERLNHEEY-GIERKEVHPHYNPADF 407
            ::|..:|::|||||....|..::      |.:.|    ..|..|...: .|:...:|..|..::.
  Rat   422 SIIGRQWILTAAHCFDGIPYPDV------WRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEG 480

  Fly   408 VNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMAT---VAGWGRTRHGQSTVPSVLQEVDVEV 469
            ..|:|||:|...:.|.:...|:|||....  |..:.|   |.|||.|:....| .::||:..:.:
  Rat   481 SYDIALIKLQTPLNYTEFQKPICLPSKAD--TNTIYTNCWVTGWGYTKERGET-QNILQKATIPL 542

  Fly   470 ISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCG 534
            :.|:.||:.:    |...|....:|||||:||.|:|:|||||||.....||..|:|:.|||.||.
  Rat   543 VPNEECQKKY----RDYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCA 603

  Fly   535 REHLPGVYTNIQRFVPWI 552
            |:..|||||.:..::.||
  Rat   604 RKEQPGVYTKVAEYIDWI 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	86/245 (35%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	87/246 (35%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	7/15 (47%)
		Tryp_SPc	390..621	CDD:214473	86/245 (35%)
		Tryp_SPc	391..621	CDD:238113	85/244 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	189	1.000	Domainoid score	I3197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44824
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810