DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8172 and Prss42

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	NP_694739.1	Gene:	Prss42 / 235628	MGIID:	2665280	Length:	335	Species:	Mus musculus

Alignment Length:	322	Identity:	105/322 - (32%)
Similarity:	161/322 - (50%)	Gaps:	52/322 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 EPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASY-RPVPG-------------------- 305
            :|.| .:|:|..:||.          .||...|:.:|.. .|.|.
Mouse    18 QPKP-CEAWAAASVLS----------TSGFPSGFSEAPRDNPPPPTRVRMSKATTRSPFMNFSLV 71

  Fly   306 CGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLS-CGGALISNRWVITAAHCVASTPNSN 369
            ||:.:.   :|:||.....|..||||::     ..|.:. |||:||:::||:|||||:.|....|
Mouse    72 CGQPFM---KIMGGVDAEEGKWPWQVSV-----RVRHMHVCGGSLINSQWVLTAAHCIYSRIQYN 128

  Fly   370 MKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYNPADFV-NDVALIRLDRNVVYKQHIIPVCLPP 433
            :|:  |:..|..|...|   ...|:...|||.::....| ||:||::|...|.:..:|.|||:|.
Mouse   129 VKV--GDRSVYRQNTSL---VIPIKTIFVHPKFSTTIVVKNDIALLKLQHPVNFTTNIYPVCIPS 188

  Fly   434 STTKL-TGKMATVAGWGRTRHGQSTVPS-VLQEVDVEVISNDRCQRWFRAA--GRREAIHDVFLC 494
            .:..: .|....|.|||:...|...||: :|||||..||..:.|....:.|  ...:.:....:|
Mouse   189 ESFPVKAGTKCWVTGWGKLVPGAPDVPTEILQEVDQNVILYEECNEMLKKATSSSVDLVKRGMVC 253

  Fly   495 AGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVM 556
             |||:.|:|:||||||||::...:.:...:|:|||||.|||:..|||||::..:..|:..|:
Mouse   254 -GYKERGKDACQGDSGGPMSCEFENKWVQVGVVSWGISCGRKGYPGVYTDVAFYSKWLIAVV 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	89/242 (37%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	90/244 (37%)
Prss42	NP_694739.1	Tryp_SPc	78..309	CDD:214473	89/241 (37%)
Prss42	NP_694739.1	Tryp_SPc	79..310	CDD:238113	89/241 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426785at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920