Protein Alignment CG8172 and Tmprss15

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_032967.1
• Gene: Tmprss15 / 19146
• MGIID: 1197523
• Length: 1069
• Species: Mus musculus
• Alignment Length: 514
• Identity: 132/514 - (25%)
• Similarity: 216/514 - (42%)
• Gaps: 107/514 - (20%)

  Fly   107 IWSCCVDKDLDAEESPHAAPVNNTSDIIHLHD----------IY------PDLSTNANKPQHHLH 155
            ||:....:..:.:.......:.|.:|::.:.|          :|      .||.:..|:
Mouse   598 IWNLNAQRGKNIQLHFQEFDLENINDVVEVRDGGEFDSLLLAVYTGPGPVKDLFSTTNR------ 656

  Fly   156 HHSGNGLSAAPSTS-STASSSARPAYPSSYY-GTKRPT----------------HYSGSNPY-KP 201
                  ::...:|: .|.....:..:.|.|| |...|.                :...|.|: :.
Mouse   657 ------MTVIFTTNMETRRKGFKANFTSGYYLGIPEPCQDDEFQCKDGNCIPLGNLCDSYPHCRD 715

  Fly   202 GSSAGGSSR--PSSSSSSSLNSWEHETGGHLG-------SISGITNHLDSFFDAESQAPLDSAGA 257
            ||......|  ..:.|::.|..:...:..|:.       .||....||.....|.|..|:.|.|.
Mouse   716 GSDEASCVRFLNGTRSNNGLVQFNIHSIWHIACAENWTTQISNEVCHLLGLGSANSSMPISSTGG 780

  Fly   258 PP-------PHEPL---PNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGE---V 309
            .|       |:..|   |:.|. :..:::.|.....:                     |||   .
Mouse   781 GPFVRVNQAPNGSLILTPSLQC-SQDSLILLQCNHKS---------------------CGEKKVT 823

  Fly   310 YTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRL 374
            ...|.:||||.....|:.||.|||......|.:|.||.:|:|:.|:::|||||     ....:..
Mouse   824 QKVSPKIVGGSDAQAGAWPWVVALYHRDRSTDRLLCGASLVSSDWLVSAAHCV-----YRRNLDP 883

  Fly   375 GEWD-VRGQEERLNHEEYGIERKEV-----HPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLP- 432
            ..|. |.|...:.|.....:.|:.|     :|||:....|||:|::.|:..|.|..:|.|:|||
Mouse   884 TRWTAVLGLHMQSNLTSPQVVRRVVDQIVINPHYDRRRKVNDIAMMHLEFKVNYTDYIQPICLPE 948

  Fly   433 PSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGY 497
            .:...:.|:..::||||..:....:...||:|.||.:|||::||:........|::    :||||
Mouse   949 ENQIFIPGRTCSIAGWGYDKINAGSTVDVLKEADVPLISNEKCQQQLPEYNITESM----ICAGY 1009

  Fly   498 KDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVM 556
            ::||.|||||||||||....:.|..|:|:.|:|:.|...:.||||..:.:|:.||:..:
Mouse  1010 EEGGIDSCQGDSGGPLMCQENNRWFLVGVTSFGVQCALPNHPGVYVRVSQFIEWIHSFL 1068

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	89/245 (36%)
Tmprss15	NP_032967.1	SEA	53..154	CDD:214554
		LDLa	228..261	CDD:197566
		CUB	270..376	CDD:412131
		MAM	392..548	CDD:459878
		CUB	569..676	CDD:395345	11/89 (12%)
		LDLa	688..722	CDD:238060	4/33 (12%)
		SR	723..816	CDD:214555	19/93 (20%)
		Tryp_SPc	830..1066	CDD:238113	89/244 (36%)