Protein Alignment CG8172 and Cfd

DIOPT Version :10

• Sequence 1: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 254
• Identity: 71/254 - (27%)
• Similarity: 114/254 - (44%)
• Gaps: 30/254 - (11%)

  Fly   315 RIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCV-ASTPNSNMKIRLGEWD 378
            ||:||......:.|:..::..:|...    |||.|:..:||::||||: ..|.:.::::.||...
Mouse    25 RILGGQEAAAHARPYMASVQVNGTHV----CGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 85

  Fly   379 VRGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKL-TGKM 442
            :...|.  ....|.::....||...|....:|:.|.:|.:|.....|:.|:.|.....:: .|.:
Mouse    86 LSAPEP--YKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTL 148

  Fly   443 ATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHD-----VFLCAGYKDGGR 502
            ..|||||...|. ...|.||.::.|.:::...|        .....||     ..:||  :...|
Mouse   149 CDVAGWGVVTHA-GRRPDVLHQLRVSIMNRTTC--------NLRTYHDGVVTINMMCA--ESNRR 202

  Fly   503 DSCQGDSGGPLTLTMDGRKTLIGLVSWGIG-CGREHLPGVYTNIQRFVPWINKVMANDN 560
            |:|:||||.||..    ...:.|:|:||.. ||....|||||.:..:..||..: .|.|
Mouse   203 DTCRGDSGSPLVC----GDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI-TNGN 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	68/246 (28%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	68/246 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)