DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	256	Identity:	92/256 - (35%)
Similarity:	136/256 - (53%)	Gaps:	18/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 PGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPN- 367
            |.||:. ..:.:||||.:...||.|||.:|.:||    ...|||:|||::|:::||||..|.||
Zfish    27 PACGKA-PLNTKIVGGTNASAGSWPWQASLHESG----SHFCGGSLISDQWILSAAHCFPSNPNP 86

  Fly   368 SNMKIRLGEWDVRGQEERL---NHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPV 429
            |:..:.||.     |.:.|   |.....:.:..|||.|..:...||:||:.|...|.:..:|.||
Zfish    87 SDYTVYLGR-----QSQDLPNPNEVSKSVSQVIVHPLYQGSTHDNDMALLHLSSPVTFSNYIQPV 146

  Fly   430 CLPPSTTKLTGKMATVAGWGRTRHGQS-TVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFL 493
            ||....:........:.|||....|.| ..|.:||||:|.::.|:.|...:   |...:|.:..:
Zfish   147 CLAADGSTFYNDTMWITGWGTIESGVSLPSPQILQEVNVPIVGNNLCNCLY---GGGSSITNNMM 208

  Fly   494 CAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINK 554
            |||...||:||||||||||:.:.........|:||:|.||...:.||||..:.::..||::
Zfish   209 CAGLMQGGKDSCQGDSGGPMVIKSFNTWVQAGVVSFGKGCADPNYPGVYARVSQYQNWISQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	87/241 (36%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	89/244 (36%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	87/241 (36%)
		Tryp_SPc	38..269	CDD:238113	89/242 (37%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587677
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740