DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8172 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	264	Identity:	97/264 - (36%)
Similarity:	133/264 - (50%)	Gaps:	30/264 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 CGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNM 370
            ||.....|.|||||:.:..|..||||:|   .|....| |||::|::||::||||||........
Zfish   288 CGSRPKFSARIVGGNLSAEGQFPWQVSL---HFQNEHL-CGGSIITSRWILTAAHCVYGIAYPMY 348

  Fly   371 KIRLGEWDVRG--QEERLNH-EEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLP 432
                  |.|..  .|..||. :.:.:|:...|..|.|....:|:||::|.:.:.:...:.|:|||
Zfish   349 ------WMVYAGLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLP 407

  Fly   433 PSTTKL-TGKMATVAGWGRTRHGQSTVPSVLQE-VDVEVISNDRCQ-----RWFRAAGRREAIHD 490
            ....:. .|||..::|||.|..|...  ||.|. ..|.:|||..|.     :.:..||
Zfish   408 NFGEQFEDGKMCWISGWGATEDGGDA--SVSQHCASVPLISNKACSQPEVYQGYLTAG------- 463

  Fly   491 VFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKV 555
             .:||||.|||.|||||||||||.........|:|..|||.||..::.|||||.|.:.:.||:..
Zfish   464 -MICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQ 527

  Fly   556 MAND 559
            |..:
Zfish   528 MERE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	91/246 (37%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	92/248 (37%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	2/3 (67%)
		Tryp_SPc	298..525	CDD:238113	91/246 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810